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Structure of the Ebola Fusion Peptide in a Membrane-mimetic Environment and the Interaction with Lipid Rafts*
The fusion peptide EBO16 (GAAIGLAWIPYFGPAA) comprises the fusion domain of an internal sequence located in the envelope fusion glycoprotein (GP2) of the Ebola virus. This region interacts with theExpand
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Structure of a Membrane-binding Domain from a Non-enveloped Animal Virus
The γ1-peptide is a 21-residue lipid-binding domain from the non-enveloped Flock House virus (FHV). Unlike enveloped viruses, the entry of non-enveloped viruses into cells is believed to occurExpand
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New cytotoxic sterol glycosides from the octocoral Carijoa (Telesto) riisei.
Two new steroidal glycosides, 3beta-O-(3'-O-acetyl-beta-D-arabinopyranosyl)-25xi-choles tan e-3beta, 5alpha,6beta,26-tetrol-26-acetate (riisein A, 2) andExpand
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Polyenic pigments from the Brazilian octocoral Phyllogorgia dilatata Esper, 1806 characterized by Raman spectroscopy
Phyllogorgia dilatata is a Brazilian endemic gorgonian with a natural color ranging from white to pale yellow. An unusual violet pigmentation has been observed in colonies with tissue damage andExpand
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Natural Products from the Gorgonian Lophogorgia punicea: Isolation and Struture Elucidation of an Unusual 17-Hydroxy Sterol
The natural products chemistry of the gorgonian Lophogorgia punicea, collected on the Southeast Brazilian coast, were investigated for the first time. Gas chromatography - mass spectral analysis ofExpand
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Conversion of wild-type p53 core domain into a conformation that mimics a hot-spot mutant.
The wild-type p53 protein can be driven into a conformation corresponding to that adopted by structural mutant forms by heterodimerization with a mutant subunit. To seek partially folded states ofExpand
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Identification of Shell Colour Pigments in Marine Snails Clanculus pharaonius and C. margaritarius (Trochoidea; Gastropoda)
Colour and pattern are key traits with important roles in camouflage, warning and attraction. Ideally, in order to begin to understand the evolution and ecology of colour in nature, it is importantExpand
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Antipredatory secosterols from the octocoral Pseudopterogorgia americana
The chemical defense of the Caribbean octocoral Pseudopterogorgia americana was investigated using feeding assays performed in aquaria and in situ with a natural assemblage of predatory fishes. UsingExpand
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Colour diversification in octocorals based on conjugated polyenes: A Raman spectroscopic view
Polyenic pigments in octocorals have been investigated by Raman spectroscopy using laser excitation at 532, 785 and 1064 nm. The spectral features suggest the structural nature of carotenoids fromExpand
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Conjugated polyenes as chemical probes of life signature: use of Raman spectroscopy to differentiate polyenic pigments
Polyenes, which are represented by carotenes, carotenoids and conjugated polyenals, are some of the most important targets for astrobiology, because they can provide strong evidence of the presenceExpand
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