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Genetic analysis among environmental strains of Balamuthia mandrillaris recovered from an artificial lagoon and from soil in Sonora, Mexico.
TLDR
High homogeneity of total protein products, and similarity in antigenic moiety among the eight new isolates and two controls was found, which indicate very low levels of genetic variation within B. mandrillaris. Expand
Copromyxa laresi n. sp. (Amoebozoa: Tubulinea) and Transfer of Cashia limacoides (Page, 1967) to Copromyxa Zopf, 1885
TLDR
Five amoeboid organisms of different origin that shared light microscopical and ultrastructural features including type and arrangement of mitochondrial cristae were subjected to phylogenetic analyses based on sequences of SSU rDNA and protein coding genes. Expand
Novel culture medium for the axenic growth of Balamuthia mandrillaris.
TLDR
A novel culture medium is developed for axenic cultivation of Balamuthia mandrillaris that is as useful as BM-3 for axenization and opens the possibility of increasing its study. Expand
Neovahlkampfia nana n. sp. Reinforcing an Underrepresented Subclade of Tetramitia, Heterolobosea
TLDR
The study provides robust genetic evidence that a newly isolated naked ameba with morphological and ultrastructural features indicative of Heterolobosea is a new species and points to the potentially dubious validity of some current nominal species of Hetteroloboseda that differ from one another in just one or two base positions. Expand
Potentially pathogenic genera of free-living amoebae coexisting in a thermal spring.
TLDR
Which potentially pathogenic free-living amoebae could be found co-inhabiting a source of natural thermal water called "Agua Caliente" (Mexico) and which could be identified as Vermamoeba vermiformis were determined. Expand
Detection of serum antibodies in children and adolescents against Balamuthia mandrillaris, Naegleria fowleri and Acanthamoeba T4.
TLDR
The statistical analysis showed different distributions among the three communities and for the three species of pathogenic free-living amoebae, including age, and Lysed and complete cells used as Balamuthia antigens gave differences in seropositivity. Expand
Acanthamoeba mauritaniensis genotype T4D: An environmental isolate displays pathogenic behavior.
TLDR
It is suggested that A. mauritaniensis genotype T4D behaves similarly to the A. castellanii strain, a nonpathogenic amoeba that can induce substantial damage to RCE1(5T5) and MDCK cells. Expand
Ultrastructural, Cytochemical, and Comparative Genomic Evidence of Peroxisomes in Three Genera of Pathogenic Free-Living Amoebae, Including the First Morphological Data for the Presence of This
TLDR
Investigation of the presence of peroxisomes in three genera of free-living amoebae from two different taxonomic groups that are known to cause fatal infections in humans indicates that they have a similar peroxin complement despite belonging to different evolutionary lineages. Expand
In Vitro Screening of the Open-Source Medicines for Malaria Venture Malaria and Pathogen Boxes To Discover Novel Compounds with Activity against Balamuthia mandrillaris
TLDR
54 hits were identified that significantly inhibited the growth of B. mandrillaris in vitro from an initial single point screen at 1 and 10 μM, which aimed to discover new leads for drug discovery by screening the open-source Medicines for Malaria Venture Malaria Box and MMV Pathogen Box, with 800 compounds total. Expand
Balamuthia mandrillaris: Further morphological observations of trophozoites by light, scanning and transmission electron microscopy.
TLDR
The observed morphological features of Balamuthia mandrillaris may reinforce the morphological knowledge of this amoeba and provide a background for further analyses. Expand
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