L. Eyer

Publications47
h-index15
Citations699
Highly Influential Citations23
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Tick-borne encephalitis in Europe and Russia: Review of pathogenesis, clinical features, therapy, and vaccines.
Tick-borne encephalitis (TBE) is an illness caused by tick-borne encephalitis virus (TBEV) infection which is often limited to a febrile illness, but may lead to very aggressive downstream… Expand
  • 64
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Electron Tomography Analysis of Tick-Borne Encephalitis Virus Infection in Human Neurons
Tick-borne encephalitis virus (TBEV) causes serious, potentially fatal neurological infections that affect humans in endemic regions of Europe and Asia. Neurons are the primary target for TBEV… Expand
  • 48
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Characterisation of Zika virus infection in primary human astrocytes
BackgroundThe recent Zika virus (ZIKV) outbreak has linked ZIKV with microcephaly and other central nervous system pathologies in humans. Astrocytes are among the first cells to respond to ZIKV… Expand
  • 23
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Arbidol (Umifenovir): A Broad-Spectrum Antiviral Drug That Inhibits Medically Important Arthropod-Borne Flaviviruses
Arthropod-borne flaviviruses are human pathogens of global medical importance, against which no effective small molecule-based antiviral therapy has currently been reported. Arbidol (umifenovir) is a… Expand
  • 61
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Structural protein analysis of the polyvalent staphylococcal bacteriophage 812
Phage 812 is a polyvalent phage with a very broad host range in the genus Staphylococcus, which makes it a suitable candidate for phage therapy of staphylococcal infections. This proteomic study,… Expand
  • 36
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Single-domain antibody fragments derived from heavy-chain antibodies: a review
Single-domain antibody (sdAb) fragments derived from heavy-chain antibodies of camelids and cartilagi- nous fish represent a new generation of therapeutic agents and immunoreagents. Due to their… Expand
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Structure-activity relationships of nucleoside analogues for inhibition of tick-borne encephalitis virus.
Tick-borne encephalitis (TBE) represents one of the most serious arboviral neuro-infections in Europe and northern Asia. As no specific antiviral therapy is available at present, there is an urgent… Expand
  • 39
  • 1
An Approach for Zika Virus Inhibition Using Homology Structure of the Envelope Protein
To find an effective drug for Zika virus, it is important to understand how numerous proteins which are critical for the virus’ structure and function interact with their counterparts. One approach… Expand
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2,4-D and IAA Amino Acid Conjugates Show Distinct Metabolism in Arabidopsis
The herbicide 2,4-D exhibits an auxinic activity and therefore can be used as a synthetic and traceable analog to study auxin-related responses. Here we identified that not only exogenous 2,4-D but… Expand
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An E460D substitution in the NS5 protein of tick-borne encephalitis virus confers resistance to the inhibitor Galidesivir (BCX4430) and also attenuates the virus for mice
The adenosine analogue Galidesivir (BCX4430), a broad-spectrum RNA virus inhibitor, has entered a Phase 1 clinical safety and pharmacokinetics study in healthy subjects and is under clinical… Expand
  • 10
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