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Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis.
This meta-analysis yielded no evidence that the serotonin transporter genotype alone or in interaction with stressful life events is associated with an elevated risk of depression in men alone, women alone, or in both sexes combined. Expand
Genetic and Environmental Factors in Relative Body Weight and Human Adiposity
Data from the Virginia 30,000, including twins and their parents, siblings, spouses, and children, were analyzed using a structural equation model (Stealth) and no evidence was found for a special MZ twin environment, thereby supporting the equal environment assumption. Expand
The genetic epidemiology of bulimia nervosa.
The liability to fully syndromal bulimia nervosa, which affects around one in 25 women at some point in their lives, is substantially influenced by both epidemiologic and genetic risk factors. Expand
Childhood adversity, monoamine oxidase a genotype, and risk for conduct disorder.
This study replicates a recent report of a genotype-environment interaction that predicts individual variation in risk for antisocial behavior in boys and finds that low monoamine oxidase A activity increased risk for conduct disorder only in the presence of an adverse childhood environment. Expand
Genetics and developmental psychopathology: 2. The main effects of genes and environment on behavioral problems in the Virginia Twin Study of Adolescent Behavioral Development.
A widespread influence of genetic factors on risk to adolescent psychopathology is supported and suggests that the contribution of different types of social influence may vary consistently across domains of measurement. Expand
Co-occurrence of abuse of different drugs in men: the role of drug-specific and shared vulnerabilities.
Evidence is found for a shared or common vulnerability factor that underlies the abuse of marijuana, sedatives, stimulants, heroin or opiates, and psychedelics that is influenced by genetic, family environmental, and nonfamily environmental factors. Expand
Genes, culture, and personality : an empirical approach
ideas about causation are crystalized in a model for the statistics that can be derived from data on various sets of relatives. The "model" represents the bridge between theory and data, byExpand
A longitudinal twin study of personality and major depression in women.
In women, the relationship between neuroticism and the liability to major depression is substantial and largely the result of genetic factors that predispose to both neuroticismand major depression. Expand
Smoking and major depression. A causal analysis.
The results suggest that the association between smoking andMD in women is not a causal one but arises largely from familial factors, which are probably genetic, that predispose to both smoking and MD. Expand
The structure of the genetic and environmental risk factors for six major psychiatric disorders in women. Phobia, generalized anxiety disorder, panic disorder, bulimia, major depression, and
These results support the following hypotheses: each major risk factor domain influences comorbidity between these disorders in a distinct manner, and most of the genetic factors that influence vulnerability to alcoholism in women do not alter the risk for development of other common psychiatric disorders. Expand