• Publications
  • Influence
[Vicissitudes of a vitamin; folic acid].
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Asymmetric distribution of arachidonic acid in the plasma membrane of human platelets. A determination using purified phospholipases and a rapid method for membrane isolation.
1. Non-lytic degradation of human platelet phospholipids have been performed using a combination of bee venom phospholipase A2 (phosphatide 2-acyl-hydrolase, EC 3.1.1.4) and Staphylococcus aureusExpand
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Phosphatidic and lysophosphatidic acid production in phospholipase C-and thrombin-treated platelets. Possible involvement of a platelet lipase.
Incubation of 32P-labelled platelets with Clostridium welchii phospholipase C greatly stimulates 32P-incorporation into phosphatidic and lysophosphatidic acids. A net synthesis is demonstrated forExpand
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Réaction de libération plaquettaire induite par la phospholipase C
Human washed-platelet suspensions are incubated with 7.5 μg/ml (final concentration) of phospholipase C from Clostridium welchii for 0 to 5 min. The enzyme is previously heated for 12 min at 56°C inExpand
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Distribution of high-density lipoprotein 2 and 3 constituents during in vitro phospholipid hydrolysis.
Human high-density lipoproteins HDL2 (d = 1.068-1.125) and HDL3 (d = 1.125-1.210) doubly labelled with [3H]cholesterol/cholesteryl ester and with [acyl-14C]phosphatidylcholine were further incubatedExpand
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A new human pathology with visceral accumulation of long-chain n-alkanes; tissue distribution of the stored compounds and pathophysiological hypotheses.
This report deals with a new human disorder characterized by the accumulation of plant long-chain n-alkanes in viscera of a human patient. Lipid analysis of tissues from an adult male after suddenExpand
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Carrier-mediated choline uptake by Krebs II ascites cells.
Krebs II ascites cells have a low affinity uptake system for choline (Km = 36 microM, Vm = 76 nmol/min per 2 X 10(8). Choline entered the cells and was rapidly phosphorylated (95% of totalExpand
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Lymphoid cell lines as a model system for the study of Wolman's disease: Enzymatic, metabolic and ultrastructural investigations
Epstein-Barr virus (EBV) transformed lymphoid cell lines (LCL) were established from blood lymphocytes of a patient affected with Wolman's disease (WD) and from her parents. These LCL showed a severeExpand
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Studies on ether phospholipids. II. Comparative composition of various tissues from human, rat and guinea pig.
The ether phospholipid composition of various tissues (brain, heart, lung, liver, kidney, testis, erythrocytes and plasma) has been investigated in human, rat and guinea pig, using a new method ofExpand
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Modification of subunit interaction in membrane‐bound acid β‐glucosidase from Gaucher disease
The radiation inactivation method has been used to determine the molecular mass of membrane‐bound acid β‐glucosidase (EC 3.2.1.21) in situ, in normal human spleen and in that of two patients withExpand
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