• Publications
  • Influence
Item, context and relational episodic encoding in humans
  • L. Davachi
  • Psychology, Biology
    Current Opinion in Neurobiology
  • 1 December 2006
Multiple routes to memory: Distinct medial temporal lobe processes build item and source memories
This work used event-related functional MRI to examine the relation between activation in distinct medial temporal lobe subregions during memory formation and the ability to later recognize an item as previously encountered and later recollect specific contextual details about the prior encounter.
Functional-Neuroanatomic Correlates of Recollection: Implications for Models of Recognition Memory
Results revealed that multiple left prefrontal cortical regions were engaged during attempts to recollect previous contextual details, regardless of the nature of the to-be-recollected details and of source recollection outcome (successful vs unsuccessful).
Perirhinal and Parahippocampal Cortices Differentially Contribute to Later Recollection of Object- and Scene-Related Event Details
The results strongly point to representational domain as a key factor determining the involvement of different MTLC subregions during successful episodic memory formation.
Hippocampal contributions to episodic encoding: insights from relational and item-based learning.
Evidence is provided that the hippocampus, while engaged during item-based working memory maintenance, differentially subserves the relational binding of items into an integrated memory trace so that the experience can be later remembered.
Selective and Shared Contributions of the Hippocampus and Perirhinal Cortex to Episodic Item and Associative Encoding
A subsequent memory paradigm that assessed successful item encoding in addition to the encoding of two distinct episodic details, providing strong evidence for a role of the hippocampus in domain-general associative encoding and raising the possibility that PrC encoding operations in conjunction with hippocampal mechanisms contribute to later recollection of presented item details.
Evidence for area CA1 as a match/mismatch detector: A high‐resolution fMRI study of the human hippocampus
Testing the theoretical role of area CA1 in match/mismatch detection found it to be sensitive to both behaviorally relevant and irrelevant changes, a key feature of an automatic comparator.
Differential Encoding Mechanisms for Subsequent Associative Recognition and Free Recall
Functional magnetic resonance imaging was used to investigate the encoding mechanisms that support later free recall and their relationship to those that support different forms of later recognition memory and found that activation in the left inferior frontal gyrus and hippocampus correlated with later associative/relational recognition.