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The 3'-terminal sequence of Escherichia coli 16S ribosomal RNA: complementarity to nonsense triplets and ribosome binding sites.
  • J. Shine, L. Dalgarno
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences…
  • 1 April 1974
It is suggested that this region of the RNA is able to interact with mRNA and that the 3'-terminal U-U-A(OH) is involved in the termination of protein synthesis through base-pairing with terminator codons. Expand
Conserved elements in the 3' untranslated region of flavivirus RNAs and potential cyclization sequences.
In all three viruses, which represent the three major serological subgroups of the mosquito-borne flaviviruses, the 3'-proximal conserved sequence element, which is found immediately adjacent to the potential 3'-terminal hairpin, is complementary to another conserved domain near the 5' end of the viral RNAs, suggesting that flavivirus RNAs can cyclize. Expand
Determinant of cistron specificity in bacterial ribosomes
Complementarity relationships between this sequence and a purine-rich tract in the ribosome binding site of different bacterial mRNAs suggest that the 3′-end of 16S RNA determines the intrinsic capacity of ribosomes to translate a particular cistron. Expand
Genome sequences of a mouse-avirulent and a mouse-virulent strain of Ross River virus.
The nucleotide sequence of the genomic RNA of a mouse-avirulent strain of Ross River virus, RRV NB5092 (isolated in 1969), has been determined and the corresponding sequence for the prototypeExpand
Partial nucleotide sequence of the Murray Valley encephalitis virus genome. Comparison of the encoded polypeptides with yellow fever virus structural and non-structural proteins.
The genome organization of Murray Valley encephalitis and yellow fever appears to be identical and the sizes of the predicted virus-coded proteins similar between the two viruses, and the existence, in flavivirus-infected cells, of two small, hydrophobic peptides, which show only limited amino acid sequence homology. Expand
Changes in the dengue virus major envelope protein on passaging and their localization on the three-dimensional structure of the protein.
The structural protein genes of three dengue type 3 isolates after intracerebral passage in mice and after passage in cultured monkey kidney and Aedes albopictus cells are sequenced and changes in the fusion characteristics of the passaged viruses were demonstrated. Expand
A comparison of the spread of Murray Valley encephalitis viruses of high or low neuroinvasiveness in the tissues of Swiss mice after peripheral inoculation.
Both viruses appeared to enter the central nervous system via the olfactory lobes, and BH3479 spread throughout the CNS in a rostral to caudal direction over 3-4 days and most BHv1-infected mice experienced a subclinical infection; the mortality rate from BHV1 infection was less than 1%. Expand
Geographic distribution and evolution of yellow fever viruses based on direct sequencing of genomic cDNA fragments.
The nucleotide sequence of an envelope protein gene fragment encoding amino acids 291 to 406 of 22 yellow fever (YF) virus strains of diverse geographic and host origins isolated over a 63 year time span is compared to offer a useful tool for the understanding of YF virus distribution and evolution. Expand
Host cell selection of Murray Valley encephalitis virus variants altered at an RGD sequence in the envelope protein and in mouse virulence.
It is proposed that the domain of E encompassing the RGD sequence is an important determinant of flavivirus pathogenicity. Expand
Sequence studies of several alphavirus genomic RNAs in the region containing the start of the subgenomic RNA.
The protein homology is sufficient, however, for deduction of the correct coding phase of the RNA and allows the alignment of the corresponding nucleic acid sequence data from different alphaviruses without knowledge of the sequence of the entire genomes. Expand