Share This Author
Minireview: kisspeptin/neurokinin B/dynorphin (KNDy) cells of the arcuate nucleus: a central node in the control of gonadotropin-releasing hormone secretion.
Recently, a subset of neurons was identified in the arcuate nucleus of the hypothalamus that colocalize three neuropeptides, kisspeptin, neurokinin B, and dynorphin, each of which has been shown to…
Variation in kisspeptin and RFamide-related peptide (RFRP) expression and terminal connections to gonadotropin-releasing hormone neurons in the brain: a novel medium for seasonal breeding in the…
It is proposed that the two RFamide peptides, kisspeptin and RFRP, act in concert, with opposing effects, to regulate the activity of GnRH neurons across the seasons, leading to the annual change in fertility and the cyclical seasonal transition from nonbreeding to breeding season.
Kisspeptin neurons in the arcuate nucleus of the ewe express both dynorphin A and neurokinin B.
Data demonstrate that, in the ewe, a high percentage of ARC kisspeptin neurons also produce dynorphin and NKB, and it is proposed that a single subpopulation of ARC neurons contains all three neuropeptides.
The Catabolic Action of Insulin in the Brain Is Mediated by Melanocortins
The data suggest that the hypothalamic melanocortin system mediates the anorexic effects of central insulin, as well as of leptin.
Bidirectional connections of the medial amygdaloid nucleus in the Syrian hamster brain: Simultaneous anterograde and retrograde tract tracing
Combined anterograde and retrograde tract tracers demonstrate that subnuclei of Me are interconnected with limbic structures in hamster brain, which may contribute to chemosensory and hormonal integration to control male sexual behavior.
Identification of a Potential Ejaculation Generator in the Spinal Cord
It is suggested that this population of lumbar spinothalamic cells plays a pivotal role in generation of ejaculatory behavior and may be part of a spinal ejaculation generator.
Fos immunoreactivity in the rat brain following consummatory elements of sexual behavior: a sex comparison
Molecular mapping of the neural pathways linking leptin to the neuroendocrine reproductive axis.
- G. Louis, Megan Greenwald-Yarnell, Rebecca A. Phillips, L. Coolen, M. Lehman, M. Myers
- 22 March 2011
Findings suggest that leptin communicates with the neuroendocrine reproductive axis via multiple populations of LepRb neurons that lie afferent to both Kiss1 and GnRH neurons.
Neurokinin 3 Receptor Immunoreactivity in the Septal Region, Preoptic Area and Hypothalamus of the Female Sheep: Colocalisation in Neurokinin B Cells of the Arcuate Nucleus but not in…
NK3R is distributed in areas of the sheep POA and hypothalamus known to be involved in the control of reproductive neuroendocrine function and the lack of NK3R in GnRH neurones suggests that the actions of NKB on GnRH neurosecretory activity in the ewe are mediated indirectly via other neurones and/or neuropeptides.
The kisspeptin/neurokinin B/dynorphin (KNDy) cell population of the arcuate nucleus: sex differences and effects of prenatal testosterone in sheep.
Sex differences in kisspeptin in the arcuate nucleus, unlike that of dynorphin and neurokinin B, are not due solely to exposure to prenatal T, suggesting the existence of different critical periods for multiple peptides coexpressed within the same neuron.