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Complete Relative Stereochemistry of Maitotoxin
By addressing the relative stereochemistry of the four acyclic portions via organic synthesis, the complete relative stereochemistry of maitotoxin (MTX) has been established as 1B. The relativeExpand
Erythrocyte arginase, pyrimidine 5'-nucleotidase (P5N), and deoxypyrimidine 5'-nucleotidase (dP5N) as indices of lead exposure.
The activities of three erythrocyte (rbc) enzymes, arginase, pyrimidine 5'-nucleotidase (P5N), and deoxypyrimidine 5'-nucleotidase (dP5N), were compared in 16 lead workers and 14 age matched controlsExpand
Erythrocyte membrane microviscosity and phospholipid composition in lead workers.
The microviscosity and fluidity of erythrocyte ghost membranes from lead workers and control subjects was measured by fluorescence polarisation using the fluorophore, 1,6-diphenyl-1,3,5-hexatrieneExpand
The Stereochemical Assignment and Conformational Analysis of the V/W-Ring Juncture of Maitotoxin
The unambiguous stereochemical assignment of the V/W-ring juncture of maitotoxin, as shown in Figure 1, was accomplished using a two-step approach:  (1) the synthesis of two diastereomeric modelsExpand
Assay of human erythrocyte pyrimidine and deoxypyrimidine 5'-nucleotidase by isocratic reversed-phase high-performance liquid chromatography.
We report a rapid and reproducible assay for activity of human erythrocyte pyrimidine 5'-nucleotidase and deoxypyrimidine 5'-nucleotidase. The nucleotides CMP, UMP, dUMP, dCMP or dTMP areExpand
Prediction of blood lead by HPLC assay of erythrocyte pyrimidine 5'-nucleotidase.
A simplified preparation of erythrocytes (rbc) for rbc pyrimidine 5'-nucleotidase (P5N) is described and correlated with blood lead. Washed but unfiltered rbc are incubated with uridine monophosphateExpand
Erythrocyte pyrimidine 5'-nucleotidase and deoxynucleotidase isozymes: metallosensitivity and kinetics.
Erythrocytes from a subject with classical pyrimidine 5'-nucleotidase (P5N) deficiency (PND) possessed typically low nucleotidase activity with uridine 5'-monophosphate (UMP) and cytidineExpand
881 ERYTHROCYTE PYRIMIDINE 5′ NUCLEOTIDASE ISOENZYMES IN CONGENITAL DEFICIENCY AND IN LEAD EXPOSURE
Red blood cell (rbc) pyrimidine 5' nucleotidase deficiency (P5N) is a cytosolic enzyme system that dephosphorylates CMP, UMP, dCMP, dUMP and dTMP. The kinetics and metallosensitivities of enzymeExpand