L. Cohen

Publications554
h-index138
Citations68,698
Highly Influential Citations3,734
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Induction of plasticity in the human motor cortex by paired associative stimulation.
TLDR
It is proposed that the induced plasticity may represent a signature of associative long-term potentiation of cortical synapses or closely related neuronal mechanisms in the human cortex.
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Depression of motor cortex excitability by low‐frequency transcranial magnetic stimulation
TLDR
Spread of excitation, which may be a warning sign for seizures, occurred in one subject and was not accompanied by increased MEP amplitude, suggesting that spread ofexcitation and amplitude changes are different phenomena and also indicating the need for adequate monitoring even with stimulations at low frequencies.
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Transcranial direct current stimulation: State of the art 2008
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Non-invasive electrical and magnetic stimulation of the brain, spinal cord, roots and peripheral nerves: Basic principles and procedures for routine clinical and research application. An updated…
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Rapid plasticity of human cortical movement representation induced by practice.
TLDR
Training rapidly, and transiently, established a change in the cortical network representing the thumb, which encoded kinematic details of the practiced movement, suggesting that this phenomenon may be regarded as a short-term memory for movement and be the first step of skill acquisition.
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A temporally asymmetric Hebbian rule governing plasticity in the human motor cortex.
TLDR
This study suggests that strict temporal Hebbian rules govern the induction of long-term potentiation/long-term depression-like phenomena in vivo in the human primary motor cortex.
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Noninvasive cortical stimulation enhances motor skill acquisition over multiple days through an effect on consolidation
TLDR
Findings support the existence of a consolidation mechanism, susceptible to anodal tDCS, which contributes to offline effects but not to online effects or long-term retention, and may hold promise for the rehabilitation of brain injury.
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Modulation of muscle responses evoked by transcranial magnetic stimulation during the acquisition of new fine motor skills.
TLDR
Trans transcranial magnetic stimulation is used to study the role of plastic changes of the human motor system in the acquisition of new fine motor skills and the effect of increased hand use without specific skill learning in subjects who played the piano at will for 2 h each day but who were not taught the five-finger exercise.
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Mechanisms of enhancement of human motor cortex excitability induced by interventional paired associative stimulation
TLDR
Findings support the view that LTP‐like mechanisms may underlie the cortical plasticity induced by IPAS, as motor evoked potentials induced by unconditioned, single TMS pulses increased after IPAS.
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Direct Current Stimulation Promotes BDNF-Dependent Synaptic Plasticity: Potential Implications for Motor Learning
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