• Publications
  • Influence
Oral cavity contains distinct niches with dynamic microbial communities.
Microbes colonize human oral surfaces within hours after delivery. During postnatal development, physiological changes, such as the eruption of primary teeth and replacement of the primary dentitionExpand
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Fusion versus Bryan Cervical Disc in two-level cervical disc disease: a prospective, randomised study
In this prospective study, our aim was to compare the functional results and radiographic outcomes of fusion and Bryan Cervical Disc replacement in the treatment of two-level cervical disc disease. AExpand
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CRISPR-Cas9 mediated efficient PD-1 disruption on human primary T cells from cancer patients
Strategies that enhance the function of T cells are critical for immunotherapy. One negative regulator of T-cell activity is ligand PD-L1, which is expressed on dentritic cells (DCs) or some tumorExpand
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Aberrant crypt foci as microscopic precursors of colorectal cancer.
  • L. Cheng, M. Lai
  • Biology, Medicine
  • World journal of gastroenterology
  • 15 December 2003
Since the first detection of aberrant crypt foci (ACF) in carcinogen-treated mice, there have been numerous studies focusing on these microscopically visible lesions both in rodents and in humans.Expand
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Identification of genes with a correlation between copy number and expression in gastric cancer
BackgroundTo elucidate gene expression associated with copy number changes, we performed a genome-wide copy number and expression microarray analysis of 25 pairs of gastric tissues.MethodsWe appliedExpand
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A prospective, randomised, controlled multicentre study comparing cervical disc replacement with anterior cervical decompression and fusion
PurposeTotal cervical artificial disc replacement (TDR) simulates normal disc structure, thus avoiding the drawbacks of anterior cervical decompression and fusion (ACDF). This prospective,Expand
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Circulating MiR-125b as a Marker Predicting Chemoresistance in Breast Cancer
Background Chemotherapy is an important component in the treatment paradigm for breast cancers. However, the resistance of cancer cells to chemotherapeutic agents frequently results in the subsequentExpand
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Berberine-induced apoptotic and autophagic death of HepG2 cells requires AMPK activation
BackgroundHepatocellular carcinoma (HCC), the primary liver cancer, is one of the most malignant human tumors with extremely poor prognosis. The aim of this study was to investigate the anti-cancerExpand
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In vivo investigation of CD133 as a putative marker of cancer stem cells in Hep‐2 cell line
Mounting evidence suggests that most tumors consist of a heterogeneous population of cells with a subset population that has the exclusive tumorigenic ability. They are called cancer stem cellsExpand
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Isolation and Characterization of Methanothermobacter crinale sp. nov., a Novel Hydrogenotrophic Methanogen from the Shengli Oil Field †
ABSTRACT Syntrophic acetate oxidation coupled with hydrogenotrophic methanogenesis is an alternative methanogenic pathway in certain thermophilic anaerobic environments such as high-temperature oilExpand
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