L. Chappell

Publications133
h-index28
Citations2,104
Highly Influential Citations73
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The biology of diplostomatid eyeflukes of fishes.
  • L. Chappell
  • Biology, Medicine
  • Journal of helminthology
  • 1 June 1995
Identification and preliminary characterization of a chitinase gene in the Autographa californica nuclear polyhedrosis virus genome.
TLDR
Phylogenetic analyses indicate that AcMNPV, or an ancestral baculovirus, acquired the chitinase gene from a bacterium via horizontal gene transfer. Expand
Fish immune responses to experimental and natural infection with helminth parasites
Abstract Selected features of the responses by fish to helminth parasites are discussed and comparison is made where appropriate with mammals. These include: (i) Factors influencing host specificity… Expand
The epidemiology of diplostomiasis in farmed rainbow trout from north-east Scotland.
TLDR
It is possible by regular cleaning and use of molluscicides to keep the intensity of diplostomiasis at such a level that rainbow trout do not become severely affected, but as with other parasitic diseases, a combination of control methods will probably be required to eradicate the disease completely from trout farms. Expand
Cercariae and diplostomules of Diplostomum spathaceum (Digenea) elicit an immune response in rainbow trout, Salmo gairdneri Richardson
TLDR
The immune response of rainbow trout to cercariae and diplostomules of Di Plostomum spathaceum was investigated and sera were tested for their cross-reactivity with the other larval stage, using an ELISA. Expand
Freshwater Snails of Africa and their Medical Importance (second edition). D. Brown. London: Taylor & Francis, 1994. x + 609pp. Price £85. ISBN 0-7484-0026-5
Studies on the infectivity of Diplostomum spathaceum in rainbow trout (Oncorhynchus mykiss).
TLDR
The infectivity and efficacy of the diplostomule migration to the lens following different routes of administration was examined and significantly more metacercariae established in the lens of fish following exposure of the fish head compared with the tail region. Expand
Diplostomum spathaceum (Rud. 1819): effects of physical factors on the infection of rainbow trout (Salmo gairdneri) by cercariae.
TLDR
It was possible to ascertain that it was migration and not penetration which was inhibited at water temperatures below 10 degrees C, suggesting that it may be a possible method of controlling diplostomiasis on fish farms. Expand
Protection of rainbow trout, Oncorhynchus mykiss (Richardson), against Diplostomum spathaceum (Digenea): the role of specific antibody and activated macrophages
TLDR
An antibody–dependent cell–mediated cytotoxic (ADCC) mechanism is proposed, conferring protection in immunized fish, supported by the finding that cercarial and diplostomule antigens are capable of activating macrophages in Immunized rainbow trout. Expand
Putative immune response of rainbow trout, Salmo gairdneri, to Diplostomum spathaceum infections
TLDR
This is the first example of a reduction in the infection rate of rainbow trout immunized against a digenean parasite, when exposed to a challenge infection. Expand
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