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MIMIC-III, a freely accessible critical care database
MIMIC-III (‘Medical Information Mart for Intensive Care’) is a large, single-center database comprising information relating to patients admitted to critical care units at a large tertiary care hospital. Expand
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The Artificial Intelligence Clinician learns optimal treatment strategies for sepsis in intensive care
Sepsis is the third leading cause of death worldwide and the main cause of mortality in hospitals1–3, but the best treatment strategy remains uncertain. In particular, evidence suggests that currentExpand
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Human cerebrovascular and ventilatory CO2 reactivity to end‐tidal, arterial and internal jugular vein PCO2
This study examined cerebrovascular reactivity and ventilation during step changes in CO2 in humans. We hypothesized that: (1) end‐tidal P  CO 2 (P  ET,CO 2 ) would overestimate arterial P  CO 2 (P Expand
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Improving the quality of ECGs collected using mobile phones: The PhysioNet/Computing in Cardiology Challenge 2011
The aim of the PhysioNet/Computing in Cardiology Challenge 2011 was to develop an efficient algorithm able to run within a mobile phone, that can provide useful feedback in the process of acquiring a diagnostically useful 12-lead ECG recordings. Expand
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Early intervention with erythropoietin does not affect the outcome of acute kidney injury (the EARLYARF trial).
We performed a double-blind placebo-controlled trial to study whether early treatment with erythropoietin could prevent the development of acute kidney injury in patients in two general intensiveExpand
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ICU admission characteristics and mortality rates among elderly and very elderly patients
PurposeThe effect of advanced age per se versus severity of chronic and acute diseases on the short- and long-term survival of older patients admitted to the intensive care unit (ICU) remainsExpand
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The eICU Collaborative Research Database, a freely available multi-center database for critical care research
We describe the eICU Collaborative Research Database, a multi-center intensive care unit (ICU)database with high granularity data for over 200,000 admissions to ICUs monitored by e ICU Programs across the United States. Expand
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Dynamic cerebral autoregulation and baroreflex sensitivity during modest and severe step changes in arterial PCO2
Changes in the partial pressure of arterial CO2 (PaCO2) regulates cerebrovascular tone and dynamic cerebral autoregulation (CA). Elevations in PaCO2 also increases autonomic neural activity and mayExpand
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Proton-pump inhibitor use is associated with low serum magnesium concentrations.
Although case reports link proton-pump inhibitor (PPI) use and hypomagnesemia, no large-scale studies have been conducted. Here we examined the serum magnesium concentration and the likelihood ofExpand
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Mechanical power of ventilation is associated with mortality in critically ill patients: an analysis of patients in two observational cohorts
PurposeMechanical power (MP) may unify variables known to be related to development of ventilator-induced lung injury. The aim of this study is to examine the association between MP and mortality inExpand
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