• Publications
  • Influence
Why sex matters for neuroscience
  • L. Cahill
  • Psychology, Medicine
  • Nature Reviews Neuroscience
  • 1 June 2006
The striking quantity and diversity of sex-related influences on brain function indicate that the still widespread assumption that sex influences are negligible cannot be justified, and probably retards progress in the field. Expand
Enhanced human memory consolidation with post-learning stress: interaction with the degree of arousal at encoding.
Cold pressor stress, which significantly elevated salivary cortisol levels, enhanced memory for emotionally arousing slides compared with the controls, but did not affect memory for relatively neutral slides, which further support the view that post-learning stress hormone-related activity interacts with arousal at initial encoding to modulate memory consolidation. Expand
Amygdala activity at encoding correlated with long-term, free recall of emotional information.
The findings support the view derived from both animal and human investigations that the AC is selectively involved with the formation of enhanced long-term memory associated with emotionally arousing events. Expand
Mechanisms of emotional arousal and lasting declarative memory
Human-subject studies confirm the prediction of animal work that the amygdala is involved with the formation of enhanced declarative memory for emotionally arousing events and suggest that the amygdaloid complex serves to influence memory-storage processes in other brain regions. Expand
Pilot study of secondary prevention of posttraumatic stress disorder with propranolol
These pilot results suggest that acute, posttrauma propranolol may have a preventive effect on subsequent PTSD. Expand
A Novel Demonstration of Enhanced Memory Associated with Emotional Arousal
The relationship between emotional arousal and long-term memory is addressed in two experiments in which subjects viewed either a relatively emotionally neutral short story or a closely matched but more emotionally arousing story and were tested for retention of the story 2 weeks later. Expand
Glucocorticoid Release and Memory Consolidation in Men and Women
Among CPS-treated male subjects, there was a significant quadratic correlation between cortisol release posttraining and subsequent memory, the first demonstration of an inverted-U relationship between activity of endogenous stress hormones and human memory. Expand
Sex influences on the neurobiology of learning and memory.
It is suggested that for some tasks, stress evokes sex differences, which are not normally observed, and that these differences are mediated largely by interactions between stress and sex hormones. Expand
Amygdala modulation of hippocampal-dependent and caudate nucleus-dependent memory processes.
The findings indicate that the modulatory role of the amygdala is not limited to either of the two different forms of memory represented in spatial and cued discriminations in a water maze, and are consistent with previous findings indicating that amygdala influences on memory storage are not mediated by lasting neural changes located within the amygdala. Expand
Beta-adrenergic activation and memory for emotional events.
It is reported here that propranolol significantly impaired memory of the emotionally arousing story but did not affect memory ofThe emotionally neutral story, which supports the hypothesis that enhanced memory associated with emotional experiences involves activation of the beta-adrenergic system. Expand