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A novel multigene family may encode odorant receptors: A molecular basis for odor recognition
The mammalian olfactory system can recognize and discriminate a large number of different odorant molecules. The detection of chemically distinct odorants presumably results from the association ofExpand
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Combinatorial Receptor Codes for Odors
The discriminatory capacity of the mammalian olfactory system is such that thousands of volatile chemicals are perceived as having distinct odors. Here we used a combination of calcium imaging andExpand
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A zonal organization of odorant receptor gene expression in the olfactory epithelium
The mechanisms by which mammals discriminate a vast array of diverse odors are poorly understood. To gain insight into the organizational strategies underlying this discriminatory capacity, we haveExpand
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A second class of chemosensory receptors in the olfactory epithelium
The mammalian olfactory system detects chemicals sensed as odours as well as social cues that stimulate innate responses. Odorants are detected in the nasal olfactory epithelium by the odorantExpand
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Information coding in the olfactory system: Evidence for a stereotyped and highly organized epitope map in the olfactory bulb
In the mammalian olfactory system, information from approximately 1000 different odorant receptor types is organized in the nose into four spatial zones. Each zone is a mosaic of randomly distributedExpand
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A Multigene Family Encoding a Diverse Array of Putative Pheromone Receptors in Mammals
The vomeronasal organ of mammals is an olfactory sensory structure that detects pheromones. It contains two subsets of sensory neurons that differentially express G alpha(o) and G alpha(i2). ByExpand
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The human olfactory receptor gene family.
Humans perceive an immense variety of chemicals as having distinct odors. Odor perception initiates in the nose, where odorants are detected by a large family of olfactory receptors (ORs). ORs haveExpand
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Information coding in the vertebrate olfactory system.
  • L. Buck
  • Biology, Medicine
  • Annual review of neuroscience
  • 1996
The olfactory systems of vertebrates are able to discriminate a vast array of structurally diverse odorants. This perceptual acuity derives from a series of information-processing events that occurExpand
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Formyl peptide receptors are candidate chemosensory receptors in the vomeronasal organ
The identification of receptors that detect environmental stimuli lays a foundation for exploring the mechanisms and neural circuits underlying sensation. The mouse vomeronasal organ (VNO), whichExpand
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A family of candidate taste receptors in human and mouse
The gustatory system of mammals can sense four basic taste qualities, bitter, sweet, salty and sour, as well as umami, the taste of glutamate. Previous studies suggested that the detection of bitterExpand
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