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Muscarinic Modulation of Striatal Dopamine, Glutamate, and GABA Release, as Measured with In Vivo Microdialysis
- I. Smolders, L. Bogaert, G. Ebinger, Y. Michotte
- Biology, Medicine
- Journal of neurochemistry
- 1 May 1997
Abstract: Intrastriatal microdialysis was used to administer muscarinic drugs in freely moving rats for 40 min at a flow rate of 2 µl/min. Administration of the nonselective agonist pilocarpine at 10… Expand
Neurochemical changes and laser Doppler flowmetry in the endothelin-1 rat model for focal cerebral ischemia
Generalized neurotransmitter overflow into the extracellular space, after cerebral ischemia, has been suggested to contribute to subsequent neuronal death. This study aims to investigate the striatal… Expand
LY377770, a novel iGlu5 kainate receptor antagonist with neuroprotective effects in global and focal cerebral ischaemia
We have evaluated the neuroprotective effects of the decahydroisoquinoline LY377770, a novel iGlu5 kainate receptor antagonist, in two models of cerebral ischaemia. Global ischaemia, induced in… Expand
On-line in vivo monitoring of endogenous quinones using microdialysis coupled with electrochemical detection.
- M. Pravda, L. Bogaert, S. Sarre, G. Ebinger, J. Kauffmann, Y. Michotte
- Chemistry, Medicine
- Analytical chemistry
- 1 July 1997
The continuous on-line monitoring of endogenous quinones has been realized for the first time in an animal model of brain ischemia induced by a vasoconstrictor peptide, endothelin-1. A microdialysis… Expand
The effects of LY393613, nimodipine and verapamil, in focal cerebral ischaemia.
- L. Bogaert, M. O'Neill, +4 authors Y. Michotte
- European journal of pharmacology
- 5 January 2001
This study evaluates the effects of N-(2-[bis (4-fluorophenyl)methoxy]ethyl)-1-butanamine hydrochloride (LY393613), a novel neuronal (N/P/Q-type) Ca(2+) channel blocker, in ischaemia. For comparison,… Expand