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Congenital adrenal hyperplasia due to steroid 21-hydroxylase deficiency: an Endocrine Society clinical practice guideline.
- P. Speiser, R. Azziz, +9 authors P. White
- The Journal of clinical endocrinology and…
- 1 September 2010
OBJECTIVE We developed clinical practice guidelines for congenital adrenal hyperplasia (CAH). PARTICIPANTS The Task Force included a chair, selected by The Endocrine Society Clinical Guidelines… Expand
Congenital adrenal hyperplasia due to steroid 21-hydroxylase deficiency: an endocrine society clinical practice guideline
Evaluation and treatment of cryptorchidism: AUA guideline.
PURPOSE Cryptorchidism is one of the most common pediatric disorders of the male endocrine glands and the most common genital disorder identified at birth. This guideline is intended to provide… Expand
Essential Role for Co-chaperone Fkbp52 but Not Fkbp51 in Androgen Receptor-mediated Signaling and Physiology*
- W. Yong, Zuocheng Yang, +9 authors W. Shou
- Biology, Medicine
- Journal of Biological Chemistry
- 16 February 2007
Fkbp52 and Fkbp51 are tetratricopeptide repeat proteins found in steroid receptor complexes, and Fkbp51 is an androgen receptor (AR) target gene. Although in vitro studies suggest that Fkbp52 and… Expand
Epithelial development in the rat ventral prostate, anterior prostate and seminal vesicle.
The prostate and seminal vesicle (SV) are androgen-dependent secretory glands of the male genital tract. The epithelial cells of these glands produce the bulk of the seminal secretions. The objective… Expand
Hypospadias and endocrine disruption: is there a connection?
Hypospadias is one of the most common congenital anomalies in the United States, occurring in approximately 1 in 250 newborns or roughly 1 in 125 live male births. It is the result of arrested… Expand
Hypospadias and urethral development.
- L. Baskin
- The Journal of urology
- 1 March 2000
PURPOSE Hypospadias is a common congenital anomaly that may be treated with surgical reconstruction. In the majority of cases the etiology remains elusive. Although androgens are clearly critical for… Expand
Hypospadias: anatomy, etiology, and technique.
Hypospadias is one of the most common congenital anomalies defined by abortive development of the urethral spongiosum, the ventral prepuce and in more severe cases penile chordee. The etiology of… Expand
Conserved and Divergent Features of Human and Mouse Kidney Organogenesis.
- N. Lindström, J. McMahon, +15 authors A. McMahon
- Biology, Medicine
- Journal of the American Society of Nephrology…
- 1 March 2018
Human kidney function is underpinned by approximately 1,000,000 nephrons, although the number varies substantially, and low nephron number is linked to disease. Human kidney development initiates… Expand
Genome-wide association analyses identify variants in developmental genes associated with hypospadias
Hypospadias is a common congenital condition in boys in which the urethra opens on the underside of the penis. We performed a genome-wide association study on 1,006 surgery-confirmed hypospadias… Expand