L. Bartolo

Publications49
h-index12
Citations361
Highly Influential Citations5
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Neuronal membrane bioreactor as a tool for testing crocin neuroprotective effect in Alzheimer’s disease
Abstract In this paper a neuronal membrane bioreactor was developed as platform for the in vitro reconstruction of a neuronal network with defined functional, geometric and neuroanatomical features.… Expand
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Influence of membrane surface properties on the growth of neuronal cells isolated from hippocampus
Abstract Membranes have become of great interest for tissue engineering application, since they offer the advantage of developing neuronal tissue that may be used in implantable or in vitro hybrid… Expand
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Oxygen transport in hollow fibre membrane bioreactors for hepatic 3D cell culture: A parametric study
Abstract Hepatic cell cultures are exploited for different applications in liver disease studies, drug toxicity testing and bioartificial liver (BAL) devices. Despite the development of various 3D… Expand
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PAN hollow fiber membranes elicit functional hippocampal neuronal network
This study focuses on the development of an advanced in vitro biohybrid culture model system based on the use of hollow fibre membranes (HFMs) and hippocampal neurons in order to promote the… Expand
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Polycaprolactone-Hydroxyapatite Composite Membrane Scaffolds for Bone Tissue Engineering
Bone tissue engineering typically involves the use of porous, bioresorbable scaffolds to serve as temporary, three-dimensional scaffolds to guide cell attachment, differentiation, proliferation, and… Expand
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Human lymphocytes cultured in 3-D bioreactors: influence of configuration on metabolite transport and reactions.
Peripheral blood lymphocytes isolated from healthy human donors' buffy coat were cultured in membrane bio-reactors (MBR) designed in two different configurations: a conventional hollow-fiber (HF)… Expand
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Biodegradable and synthetic membranes for the expansion and functional differentiation of rat embryonic liver cells.
The insufficient availability of donor organs for orthotopic liver transplantation worldwide has urgently increased the requirement for new therapies for acute and chronic liver disease. The creation… Expand
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Coupled transport of amino acids through a supported liquid membrane. I. Experimental optimization
Abstract Some experimental aspects on separation, concentration and purification of amino acids through supported liquid membranes, by using D - L -phenylalanine as a model, are described. The… Expand
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Membrane bioreactors for biotechnology and medical applications
ABSTRACT In this chapter we will discuss the properties and applications of bioartificial hybrid systems used in biotechnological and medical applications. In the first part we will focused on… Expand
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Human hepatocyte functions in a galactosylated membrane bioreactor
Abstract This paper reports on the performance of galactosylated polyethersulphone (PES) membrane bioreactor that enables the long-term maintenance of liver-specific functions of human hepatocytes… Expand
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