L. B. Din
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Goniothalamin induces apoptosis in vascular smooth muscle cells.
- K. Chan, N. Rajab, +4 authors S. Inayat-Hussain
- Medicine, Chemistry
- Chemico-biological interactions
- 1 February 2006
Restenosis represents a major impediment to the success of coronary angioplasty. Abnormal proliferation of vascular smooth muscle cells (VSMCs) has been shown to be an important process in the… Expand
Goniothalamin induces coronary artery smooth muscle cells apoptosis: the p53-dependent caspase-2 activation pathway.
- Kok Meng Chan, N. Rajab, D. Siegel, L. B. Din, D. Ross, S. Inayat-Hussain
- Medicine, Biology
- Toxicological sciences : an official journal of…
- 1 August 2010
Goniothalamin (GN), a styryl-lactone isolated from Goniothalamus andersonii, has been demonstrated to possess antirestenostic properties by inducing apoptosis on coronary artery smooth muscle cells… Expand
Altholactone, a novel styryl-lactone induces apoptosis via oxidative stress in human HL-60 leukemia cells.
Plant styryl-lactone derivatives isolated from Goniothalamus sp. are potential compounds for cancer chemotherapy. In this study, we have examined the mechanisms of apoptosis induced by altholactone,… Expand
Synthesis of silver nanoparticles with antibacterial activity using the lichen Parmotrema praesorediosum
- Ropisah Mie, M. Samsudin, L. B. Din, A. Ahmad, N. Ibrahim, S. N. A. Adnan
- Materials Science, Medicine
- International journal of nanomedicine
- 19 December 2013
Development of a green chemistry process for the synthesis of silver nanoparticles has become a focus of interest. This would offer numerous benefits, including ecofriendliness and compatibility for… Expand
A survey on phytochemical and bioactivity of plant extracts from Malaysian forest reserves
Methanolic extracts of leaves from plants collected from two different forest reserves, namely, Gunung Stong, Dabong, Kelantan and Ulu Muda, Kedah in Malaysia were subjected to a study in… Expand
Triterpenes from the Root Bark of Phyllanthus Columnaris
Phytochemical study on the root bark of Phyllanthus columnaris obtain from Paula Langkawi has been conducted. The separations of the chemical components were carried out by different chromatography… Expand
Chemical Composition, Antioxidant, and Antibacterial Activities of Essential Oils from Etlingera brevilabrum Valeton
Essential oils from fresh parts of Etlingera brevilabrum Valeton (Zingiberaceae) including rhizome, stolon, stem, and leaves were hydrodistilled, and studied for their chemical composition,… Expand
Caspases‐3 and ‐7 are activated in goniothalamin‐induced apoptosis in human Jurkat T‐cells
Goniothalamin, a plant styrylpyrone derivative isolated from Goniothalamus andersonii, induced apoptosis in Jurkat T‐cells as assessed by the externalisation of phosphatidylserine. Immunoblotting… Expand
Evaluation of the cytotoxic and genotoxic effects of goniothalamin in leukemic cell lines
The cytotoxic and genotoxic effects of goniothalamin, a plant styryllactone, were evaluated using the 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay and the Alkaline… Expand