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Antiophidian properties of the aqueous extract of Mikania glomerata.
Aqueous extracts, prepared from dried or fresh roots, stems or leaves of Mikania glomerata, a plant found in Mata Atlântica in Southeastern Brazil, were able to efficiently neutralize differentExpand
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Antinociceptive and anti-inflammatory activities of Tabernaemontana catharinensis
In this work we describe the analgesic, anti-inflammatory and toxic activities as well as the phytochemical profile of the ethanol extract from Tabernaemontana catharinensis A. DC. (Apocynaceae) stemExpand
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Descriptive and functional neuroanatomy of locus coeruleus-noradrenaline-containing neurons involvement in bradykinin-induced antinociception on principal sensory trigeminal nucleus
The present study was carried out in Wistar rats, using the jaw-opening reflex and dental pulp stimulation, to investigate noradrenaline- and serotonin-mediated antinociceptive circuits. The effectsExpand
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Development of Anatomophysiologic Knowledge Regarding the Cardiovascular System: From Egyptians to Harvey
Our knowledge regarding the anatomophysiology of the cardiovascular system (CVS) has progressed since the fourth millennium BC. In Egypt (3500 BC), it was believed that a set of channels areExpand
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Contextual considerations in implementing problem-based learning approaches in a Brazilian medical curriculum: the UNAERP experience
Background Despite being a well-established pedagogical approach in medical education, the implementation of problem-based learning (PBL) approaches hinges not only on educational aspects of theExpand
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Brain sites involved in the antinociceptive effect of bradykinin in rats
The localization of brain sites where bradykinin (BK) induces its antinociceptive effect in rats, was studied using as index the threshold for the jaw‐opening reflex elicited by the dental pulpExpand
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When a misperception favors a tragedy: Carlos Chagas and the Nobel Prize of 1921.
Carlos Chagas, the discoverer of Chagas' disease was nominated to the Nobel Prize in 1921, but none did win the prize in that year. As a leader of a young scientist team, he discovered all aspects ofExpand
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Could Carlos Chagas' assumption on the relationship between goiter and chronic Chagas heart disease be correct? A historical reappraisal.
In 1910, Chagas divided the clinical manifestations of the chronic form of Chagas disease according to heart, Central Nervous System, and thyroid involvement, particularly the presence of goiter.Expand
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Carlos Chagas Discoveries as a Drop Back to Scientific Construction of Chronic Chagas Heart Disease
The scientific construction of chronic Chagas heart disease (CCHD) started in 1910 when Carlos Chagas highlighted the presence of cardiac arrhythmia during physical examination of patients withExpand
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Estudo clínico para validação da eficácia de pomada contendo barbatimão (Stryphnodendron adstringens (Mart.) Coville)* na cicatrização de úlceras de decúbito
O extrato aquoso de Stryphnodendron adstringens e tradicionalmente utilizado no Brasil como cicatrizante. Estudo clinico conduzido por seis meses teve por objetivo avaliar a eficacia de umExpand
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