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Mild cognitive impairment – beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment
The First Key Symposium was held in Stockholm, Sweden, 2–5 September 2003. The aim of the symposium was to integrate clinical and epidemiological perspectives on the topic of Mild CognitiveExpand
Transfer of Learning After Updating Training Mediated by the Striatum
We demonstrate transfer to a 3-back test of working memory after 5 weeks of training in updating in a striatal region that also was recruited pretraining. Expand
A theoretical framework for the study of adult cognitive plasticity.
Does plasticity contribute to adult cognitive development, and if so, in what ways? The vague and overused concept of plasticity makes these controversial questions difficult to answer. In thisExpand
A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised
BACKGROUND Modifiable vascular and lifestyle-related risk factors have been associated with dementia risk in observational studies. In the Finnish Geriatric Intervention Study to Prevent CognitiveExpand
Plasticity of executive functioning in young and older adults: immediate training gains, transfer, and long-term maintenance.
The authors investigated immediate training gains, transfer effects, and 18-month maintenance after 5 weeks of computer-based training in updating of information in working memory in young and olderExpand
Memory aging and brain maintenance
Episodic memory and working memory decline with advancing age. Nevertheless, large-scale population-based studies document well-preserved memory functioning in some older individuals. The influentialExpand
Stability, growth, and decline in adult life span development of declarative memory: cross-sectional and longitudinal data from a population-based study.
Five-year changes in episodic and semantic memory were examined in a sample of 829 participants (35-80 years). A cohort-matched sample (N=967) was assessed to control for practice effects. ForExpand
Age-related differences in white matter microstructure: Region-specific patterns of diffusivity
We collected MRI diffusion tensor imaging data from 80 younger (20-32 years) and 63 older (60-71 years) healthy adults. Expand
Predictors of progression from mild cognitive impairment to Alzheimer disease
Objective: To determine the occurrence of neuropsychiatric symptomatology and the relation to future development of Alzheimer disease (AD) in persons with and without mild cognitive impairment (MCI).Expand
Working-memory training in younger and older adults: training gains, transfer, and maintenance
Working memory (WM), a key determinant of many higher-order cognitive functions, declines in old age. Current research attempts to develop process-specific WM training procedures, which may lead toExpand