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The Host Immune Response to Scedosporium/Lomentospora
TLDR
Although many advances have been made, many aspects remain to be elucidated and more research is necessary to shed light on the immune response to Scedosporium/Lomentospora, since an understanding of the mechanisms involved is of great interest in developing more effective strategies against them. Expand
Melanin and pyomelanin in Aspergillus fumigatus: from its genetics to host interaction
TLDR
The aim of this review is to present the current knowledge of the genetic basis and metabolic pathways of melanin production, their activation, function, and interaction with the host immune system. Expand
Fast SARS-CoV-2 detection protocol based on RNA precipitation and RT-qPCR in nasopharyngeal swab samples
TLDR
This simple protocol allows SARS-CoV-2 testing independently of commercial kit providers in a time and cost-effective manner and can be readily implemented in research and/or diagnostic laboratories worldwide, provided that patient confidentiality and researcher safety are ensured. Expand
Study of Humoral Responses against Lomentospora/Scedosporium spp. and Aspergillus fumigatus to Identify L. prolificans Antigens of Interest for Diagnosis and Treatment
TLDR
This study identifies antigens of L. prolificans that can be considered as potential candidates for use in diagnosis and as therapeutic targets and the production of vaccines. Expand
The monoclonal antibody Ca37, developed against Candida albicans alcohol dehydrogenase, inhibits the yeast in vitro and in vivo
TLDR
The Ca37 monoclonal antibody proved to be effective against C. albicans, both in vitro and in vivo, and to act together with antifungal drugs, suggesting Adh proteins could be interesting therapeutic targets against this pathogen. Expand
ELISA Test for the Serological Detection of Scedosporium/Lomentospora in Cystic Fibrosis Patients
TLDR
Although more research is needed to reach a standardized method, this ELISA platform offers a rapid, low-cost and easy solution to detect these elusive fungi through minimally invasive sampling, allowing the monitoring of the humoral response to fungal presence. Expand
Identification of Mucor circinelloides antigens recognized by sera from immunocompromised infected mice.
TLDR
The identified proteins are well known fungal antigens and, therefore, these findings can be useful for future research into alternatives for the diagnosis and treatment of mucormycosis. Expand