• Publications
  • Influence
Journal of materials science: materials in medicine.
  • L. Ambrosio
  • Medicine
    Journal of materials science. Materials in…
  • 2003
The journal examines the metals, ceramics, polymers and composites used in orthopaedic, maxillo-facial, cardiovascular, neurological, ophthalmic and dental applications.
Poly-epsilon-caprolactone/hydroxyapatite composites for bone regeneration: in vitro characterization and human osteoblast response.
PCL represents a potential candidate as an efficient substrate for bone substitution through an accurate balance between structural/ mechanical properties of polymer and biological activities and was found to improve osteoconduction compared to the PCL alone.
The effect of matrix composition of 3D constructs on embryonic stem cell differentiation.
The data suggest that matrix composition has an important role in EBs development and that it is possible to influence stem cell differentiation toward preferential pattern, by modulating the physical and biochemical properties of the scaffold.
Bioactive scaffolds for bone and ligament tissue
The manipulation of structural parameters in the design of scaffolds and their bioactivation, through the incorporation of soluble and insoluble signals capable of promoting cell activities, are discussed as possible strategies to improve the formation of new tissues both in vitro and in vivo.
Novel superabsorbent cellulose‐based hydrogels crosslinked with citric acid
This work is focused on the preparation of new environmentally friendly hydrogels derived from cellulose and hence originating from renewable resources and characterized by biodegradable properties.
Hyaluronic acid hydrogel in the treatment of osteoarthritis.
The results obtained showed the Hyal 50% injections improved chondrocytes density and matrix appearance, and the permanence in situ of the hydrogel was longer than that of the linear Hyal.
Polymer-based composite scaffolds for tissue engineering.
This review aims at stressing the importance of polymer-based composite materials to make multifunctional scaffolds for tissue engineering, with a special focus on bone, ligaments, meniscus and cartilage.
Chitosan-mediated stimulation of macrophage function.
The present investigation demonstrates that chitosan has an in vitro stimulatory effect on both macrophage nitric oxide (NO) production and chemotaxis and strengthens the hypothesis that in vivo experiments strengthen this hypothesis.
The first systematic analysis of 3D rapid prototyped poly(ε-caprolactone) scaffolds manufactured through BioCell printing: the effect of pore size and geometry on compressive mechanical behaviour and
The obtained results clearly demonstrate the potential of the BioCell Printing process to produce 3D scaffolds with reproducible well organized architectures and tailored mechanical properties.
Optimizing PANi doped electroactive substrates as patches for the regeneration of cardiac muscle
Preliminary results concur to promise the development of electroactive biodegradable substrates able to efficiently stimulate the basic cell mechanisms, paving the way towards a new generation of synthetic patches for the support of the regeneration of damaged myocardium.