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Axis I psychiatric comorbidity and its relationship to historical illness variables in 288 patients with bipolar disorder.
TLDR
Comorbid lifetime and current axis I disorders in 288 patients with bipolar disorder and the relationships of these comorbid disorders to selected demographic and historical illness variables showed associations with earlier age at onset of affective symptoms and syndromal bipolar disorder. Expand
The functional neuroanatomy of bipolar disorder: a consensus model.
TLDR
A consensus model of the functional neuroanatomy of bipolar I disorder is developed based upon the participants' work as well as that of others to provide a potential substrate to guide future investigations and areas needing additional focus are identified. Expand
Factors associated with suicide attempts in 648 patients with bipolar disorder in the Stanley Foundation Bipolar Network.
TLDR
It is indicated that a history of suicide attempts is associated with a more difficult course of bipolar disorder and the occurrence of more psychosocial stressors at many different time domains. Expand
Evidence for deficient modulation of amygdala response by prefrontal cortex in bipolar mania
TLDR
Compared with healthy subjects, manic patients had a significantly reduced VLPFC regulation of amygdala response during the emotion labeling task, suggesting that reductions in inhibitory frontal activity in these patients may lead to an increased reactivity of the amygdala. Expand
The Stanley Foundation Bipolar Treatment Outcome Network. II. Demographics and illness characteristics of the first 261 patients.
TLDR
The SFBN represents a sample of predominantly BP I patients largely recruited from the community who will be followed in detail longitudinally, participate in clinical trials, and thus help advance the understanding and treatment of this life-threatening medical disorder. Expand
Early physical and sexual abuse associated with an adverse course of bipolar illness
TLDR
Greater appreciation of the association of early traumatic experiences and an adverse course of bipolar illness should lead to preventive and early intervention approaches that may lessen the associated risk of a poor outcome. Expand
Pharmacologic management of psychiatric illness during pregnancy: dilemmas and guidelines.
TLDR
Exposure to certain psychotropic drugs in utero may increase the risk for some specific congenital anomalies, but the rate of occurrence of these anomalies even with the increased risk remains low. Expand
Placental passage of antidepressant medications.
TLDR
Umbilical cord concentrations of antidepressants and their metabolites were almost invariably lower than corresponding maternal concentrations, suggesting that sertraline may produce less fetal medication exposure than fluoxetine near delivery. Expand
Olanzapine versus divalproex sodium for the treatment of acute mania and maintenance of remission: A 47-week study
TLDR
In this 47-week study of acute bipolar mania, symptomatic remission occurred sooner and overall mania improvement was greater for olanzapine than for divalproex, but rates of bipolar relapse did not differ. Expand
Relapse of Major Depression During Pregnancy in Women Who Maintain or Discontinue Antidepressant Treatment
TLDR
Pregnancy is not “protective” with respect to risk of relapse of major depression, and women with histories of depression who are euthymic in the context of ongoing antidepressant therapy should be aware of the association of depressive relapse during pregnancy with antidepressant discontinuation. Expand
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