Skip to search formSkip to main contentSkip to account menu
Astrocytes and Glioblastoma cells release exosomes carrying mtDNA
TLDR
Evidence is provided that bonafide exosomes, constitutively released by Glioblastoma cells and Astrocytes, can carry mtDNA, which can be transferred between cells, which may help the understanding of some diseases due to mitochondrial alterations.
View on Springer
Coaggregation, Cointernalization, and Codesensitization of Adenosine A2A Receptors and Dopamine D2Receptors*
TLDR
The results give a molecular basis for adenosine-dopamine antagonism at the membrane level and have implications for treatment of Parkinson's disease and schizophrenia, in which D2R are involved.
View on Publisher
Glucocorticoid receptor immunoreactivity in monoaminergic neurons of rat brain.
A monoclonal antibody against the rat liver glucocorticoid receptor was used in combination with rabbit antibodies against tyrosine hydroxylase, phenylethanolamine N-methyltransferase, and…
View on PubMed
Detection of heteromerization of more than two proteins by sequential BRET-FRET
TLDR
Using SRET, complexes of cannabinoid CB1, dopamine D2 and adenosine A2A receptors in living cells are identified and will allow us to better understand how signals are integrated at the molecular level.
View on Nature
The discovery of central monoamine neurons gave volume transmission to the wired brain
View on Elsevier
Targeting adenosine A2A receptors in Parkinson's disease
View on Elsevier
Intercellular communication in the brain: Wiring versus volume transmission
View on Elsevier
Dopamine D1 and adenosine A1 receptors form functionally interacting heteromeric complexes.
TLDR
The A(1)R/D( 1)R heteromerization may be one molecular basis for the demonstrated antagonistic modulation of A(2)R of D(1]R receptor signaling in the brain and seems to be essential for the blockade of A-1-R agonist-induced A(3)R-induced coclustering and for the desensitization of the D(0)R agonists cAMP accumulation.
View on PubMed
Understanding wiring and volume transmission
View on Elsevier
Mapping of glucocorticoid receptor immunoreactive neurons in the rat tel- and diencephalon using a monoclonal antibody against rat liver glucocorticoid receptor.
TLDR
It is suggested that the hypothalamic GR may be involved in the regulation of especially CRF secretion but also in the secretion of other anterior pituitary hormones such as TRH and somatostatin.
View on PubMed
...
...
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License