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- Tanya M. Teslovich, Kiran Musunuru, +205 authors Sekar Kathiresan
- Nature
- 2010
Plasma concentrations of total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol and triglycerides are among the most important risk factors for coronary artery… (More)
- Hana Lango Allen, Karol Estrada, +290 authors Joel Hirschhorn
- Nature
- 2010
Most common human traits and diseases have a polygenic pattern of inheritance: DNA sequence variants at many genetic loci influence the phenotype. Genome-wide association (GWA) studies have… (More)
- Caroline Fox, Joseph M. Massaro, +9 authors Christopher J. O'Donnell
- Circulation
- 2007
BACKGROUND
Visceral adipose tissue (VAT) compartments may confer increased metabolic risk. The incremental utility of measuring both visceral and subcutaneous abdominal adipose tissue (SAT) in… (More)
- Adam E Locke, Bratati Kahali, +478 authors Elizabeth K. Speliotes
- Nature
- 2015
Obesity is heritable and predisposes to many diseases. To understand the genetic basis of obesity better, here we conduct a genome-wide association study and Metabochip meta-analysis of body mass… (More)
- Heribert Schunkert, Inke R. König, +163 authors Jeanette Erdmann
- Nature Genetics
- 2011
We performed a meta-analysis of 14 genome-wide association studies of coronary artery disease (CAD) comprising 22,233 individuals with CAD (cases) and 64,762 controls of European descent followed by… (More)
- Cristen J. Willer, Ellen M. Schmidt, +256 authors Gonçalo R. Abecasis
- Nature Genetics
- 2013
Levels of low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, triglycerides and total cholesterol are heritable, modifiable risk factors for coronary artery… (More)
- Sekar Kathiresan, Cristen J. Willer, +58 authors L. Adrienne Cupples
- Nature Genetics
- 2009
Blood low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol and triglyceride levels are risk factors for cardiovascular disease. To dissect the polygenic basis of… (More)
- Lindsay A. Farrer, L. Adrienne Cupples, +7 authors Cornelia M van Duijn
- JAMA
- 1997
OBJECTIVE
To examine more closely the association between apolipoprotein E (APOE) genotype and Alzheimer disease (AD) by age and sex in populations of various ethnic and racial denominations.
DATA… (More)
- Iris M. Heid, Anne U. Jackson, +297 authors Cecilia M. Lindgren
- Nature Genetics
- 2011
Iris M Heid, Anne U Jackson, Joshua C Randall, Thomas W Winkler, Lu Qi, Valgerdur Steinthorsdottir, Gudmar Thorleifsson, M Carola Zillikens, Elizabeth K Speliotes, Reedik Mägi, Tsegaselassie… (More)
- Karol Estrada, Unnur Styrkarsdottir, +178 authors Fernando Rivadeneira
- Skeletal Radiology
- 2012
Bone mineral density (BMD) is the most widely used predictor of fracture risk. We performed the largest meta-analysis to date on lumbar spine and femoral neck BMD, including 17 genome-wide… (More)