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Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substrates
- N. Balaban, U. Schwarz, +8 authors B. Geiger
- Materials Science, Medicine
- Nature Cell Biology
- 1 May 2001
Mechanical forces play a major role in the regulation of cell adhesion and cytoskeletal organization. In order to explore the molecular mechanism underlying this regulation, we have investigated the… Expand
Hierarchical assembly of cell-matrix adhesion complexes.
- R. Zaidel-Bar, M. Cohen, L. Addadi, B. Geiger
- Biology, Medicine
- Biochemical Society transactions
- 1 June 2004
The adhesion of cells to the extracellular matrix is a dynamic process, mediated by a series of cell-surface and matrix-associated molecules that interact with each other in a spatially and… Expand
Mollusk Shell Formation: A Source of New Concepts for Understanding Biomineralization Processes
- L. Addadi, D. Joester, F. Nudelman, S. Weiner
- Chemistry
- 18 April 2006
Interactions between acidic proteins and crystals: stereochemical requirements in biomineralization.
Acidic matrix macromolecules are intimately involved in biological crystal growth. In vitro experiments, in which crystals of calcium dicarboxylate salts were grown in the presence of aspartic… Expand
Mollusc larval shell formation: amorphous calcium carbonate is a precursor phase for aragonite.
- I. Weiss, N. Tuross, L. Addadi, S. Weiner
- Biology, Medicine
- The Journal of experimental zoology
- 1 October 2002
The larval shells of the marine bivalves Mercenaria mercenaria and Crassostrea gigas are investigated by polarized light microscopy, infrared spectroscopy, Raman imaging spectroscopy, and scanning… Expand
Taking Advantage of Disorder: Amorphous Calcium Carbonate and Its Roles in Biomineralization
Amorphous calcium carbonate (ACC) in its pure form is highly unstable, yet some organisms produce stable ACC, and cases are known in which ACC functions as a transient precursor of more stable… Expand
Amorphous calcium carbonate transforms into calcite during sea urchin larval spicule growth
- E. Beniash, J. Aizenberg, L. Addadi, S. Weiner
- Biology
- Proceedings of the Royal Society of London…
- 22 March 1997
Sea urchin larvae form an endoskeleton composed of a pair of spicules. For more than a century it has been stated that each spicule comprises a single crystal of the CaCO3 mineral, calcite. We show… Expand
Design strategies in mineralized biological materials
Organisms have been producing mineralized skeletons for the past
550
million years. They have evolved many different strategies for
improving
these materials at almost all hierarchical levels… Expand
Structure of the nacreous organic matrix of a bivalve mollusk shell examined in the hydrated state using cryo-TEM.
- Y. Levi-Kalisman, G. Falini, L. Addadi, S. Weiner
- Chemistry, Medicine
- Journal of structural biology
- 1 July 2001
During mollusk shell formation, the mineral phase forms within an organic matrix composed of beta-chitin, silk-like proteins, and acidic glycoproteins rich in aspartic acid. The matrix is widely… Expand
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