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MAPMAKER: an interactive computer package for constructing primary genetic linkage maps of experimental and natural populations.
With the advent of RFLPs, genetic linkage maps are now being assembled for a number of organisms including both inbred experimental populations such as maize and outbred natural populations such asExpand
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Corrigendum to “MAPMAKER: An interactive computer package for constructing primary genetic linkage maps of experimental and natural populations” [Genomics 1 (1987) 174–181]
Corrigendum to “MAPMAKER: An interactive computer package for constructing primary genetic linkage maps of experimental and natural populations” [Genomics 1 (1987) 174–181] Eric S. Lander , PhilipExpand
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Computational de novo discovery of distinguishing genes for biological processes and cell types in complex tissues
Bulk tissue samples examined by gene expression studies are usually heterogeneous. The data gained from these samples display the confounding patterns of mixtures consisting of multiple cell types orExpand
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Finding, Evaluating, and Counting DNA Physical Maps
Finding, Evaluating, and Counting DNA Physical Maps by Lee Aaron Newberg Doctor of Philosophy in Computer Science University of California at Berkeley Professor Richard M. Karp, Chair TheExpand
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Finding Protein Binding Sites Using Volunteer Computing Grids
This paper describes initial work in the development of the DNA@Home volunteer computing project, which aims to use Gibbs sampling for the identification and location of DNA control signals on fullExpand
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A highly parallel next-generation DNA sequencing data analysis pipeline in Hadoop
The era of precision medicine is best exemplified by the growing reliance on next-generation sequencing (NGS) technologies to provide improved disease diagnosis and targeted therapeutic selection.Expand
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Finding a most likely clone ordering from oligonucleotide hybridization data.
Using an extension of a statistical model given by E. Lander and M. Waterman, we define the a posteriori probability of a clone ordering based upon oligonucleotide hybridization data. We giveExpand
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Abstract 3589: A systematic approach toward gene annotation of the hallmarks of cancer
The hallmarks of cancer consist of ten categories that serve as an organizing principle and framework for understanding neoplastic disease. The ten hallmarks include activating invasion andExpand
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Implementing a Student Allele Database via the World Wide Web ( Extended
We describe the design and implementation of the Human Genome Diversity Project’s Student Allele Database Facility and its interface via the World-Wide Web. The electronic lab bench is 80% completeExpand
A computational system for identifyingcis-regulatory elements in closely related genomes
Scientists are only beginning to develop methods for whole genome comparisons. Computational methods which do not incorporate evolutionary relationships in their models are inadequate when there isExpand