• Publications
  • Influence
Spectrophotometric determination of the total flavonoid content in Ocimum basilicum L. (Lamiaceae) leaves
TLDR
The optimization of a simple, fast and precise method for the determination of the TFC in leaves of O. basilicum is allowed, which can be used to support the quality assessment of this herbal material.
Phytochemical profile of different anatomical parts of jambu (Acmella oleracea (L.) R.K. Jansen): A comparison between hydroponic and conventional cultivation using PCA and cluster analysis.
TLDR
In both crop systems, the leaves of jambu cultivated in hydroponic and conventional systems showed the highest total phenolic content, total flavonoid content and in vitro antioxidant capacity.
ESI-MS2 and Anti-inflammatory Studies of Cyclopropanic Triterpenes. UPLC-ESI-MS and MS2 Search of Related Metabolites from Donella ubanguiensis.
TLDR
The fragmentation behaviour of these metabolites will serve as a fingerprint to search and characterise triterpenes congeners in fruits, bark and wood crude extracts of D. ubanguiensis and Donella species deserve more investigation since metabolites related to the anti-inflammatory compound (DA A) could be identified.
ESI-QTof-MS characterization of hirsutinolide and glaucolide sesquiterpene lactones: fragmentation mechanisms and differentiation based on Na+ /H+ adducts interactions in complex mixture.
TLDR
The differentiation strategy based on the nature of the complex SL-adducts and their MS/MS fragmentation pattern were successfully applied for the chemical characterization of the extract from Vernonanthura tweedieana using UPLC-ESI-HRMS/MS.
Antinociceptive and anti-inflammatory activities of the Jatropha isabellei dichloromethane fraction and isolation and quantitative determination of jatrophone by UFLC-DAD
TLDR
The DFJi displayed antinociceptive and antiedematogenic activities, representing a promising plant product for the arthritis treatment, and an analytical method to quantify the diterpene jatrophone was developed.
A single-step isolation by centrifugal partition chromatography of the potential anti-inflammatory glaucolide B from Lepidaploa chamissonis.
TLDR
Isolated for the first time from L. chamissonis leaves, glaucolide B presented a significant inhibitory effect on both NO and IL-6 secretion under non-toxic concentrations and proved a simple and effective tool for the isolation of 1 within few hours.
Simple and fast UPLC-MS method for quantifying the anti-inflammatory candidate 5'-methoxynobiletin in rat plasma: Validation and application in a preliminary pharmacokinetic study.
TLDR
For the first time, using the validated UPLC-MS bioanalytical method, the plasma pharmacokinetics of 5'-MeONB following 2 mg/kg intravenous bolus dosing to Wistar rats was characterized allowing the determination of the parameters describing drug distribution and elimination.