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Evaluation of advanced fibrosis measured by transient elastography after hepatitis C virus protease inhibitor-based triple therapy
TLDR
In patients with advanced fibrosis measured by transient elastography at the beginning of protease inhibitor-based therapy with sustained virological response, liver stiffness was significantly reduced 24 weeks after treatment, suggesting the possibility of liver cirrhosis evidenced by liver stiffness regression after sustained virology response in a significant proportion of patients. Expand
Efficacy of intraoperative surgical irrigation with polihexanide and nitrofurazone in reducing bacterial load after nail removal surgery.
TLDR
Intraoperative irrigation with 0.1% polihexanide substantially reduced the bacterial load and subsequent infections, highlighting the importance of an irrigation step in nail avulsion surgery. Expand
Preoperative skin and nail preparation of the foot: comparison of the efficacy of 4 different methods in reducing bacterial load.
Background Orthopedic surgical procedures involving the foot and ankle are associated with high rates of infection. The optimal method of preparing the skin and nails for foot and ankle surgeryExpand
Changes in brain kynurenine levels via gut microbiota and gut‐barrier disruption induced by chronic ethanol exposure in mice
TLDR
Several parameters of gut‐barrier and of peripheral and central Trp metabolism following 2 different EtOH consumption patterns in mice, the binge model, drinking in the dark (DID), and the chronic intermittent (CI) consumption paradigm were analyzed. Expand
Efficacy of Preoperative and Intraoperative Skin and Nail Surgical Preparation of the Foot in Reducing Bacterial Load
TLDR
Comparing the antiseptic efficacy of two skin pretreatment methods before toenail avulsion surgery found both methods to be effective at reducing the initial bacterial load when used at pretreatment, but the reduction in bacterial load was lost after the nailAvulsion surgery. Expand
Effectiveness of surgical hand antisepsis using chlorhexidine digluconate and parachlorometaxylenol hand scrub
TLDR
A randomized, double-blind, controlled crossover trial to compare the bacterial loads on fingertips and fingernails after use of antiseptic test products found chlorhexidine digluconate 4% and PCMX 3% had similar bactericidal efficacy, but they failed to meet the EN 12791 efficacy standard. Expand
Total nail ablation for onychodystrophy with optimized gauze-phenol application.
TLDR
Phenol-based total nail ablation with specific gauze application is safe, inexpensive and has a high rate of patient satisfaction, according to a limited number of participants in this study. Expand
Importance of pre-operative skin and nail preparation of the foot and intra-operative surgical irrigation in reducing infection after surgical nail avulsion
TLDR
Clinical studies highlight the importance of utilizing an antiseptic approach at multiple stages of phenol-based nail surgery, to combat the high rate of infection that can result from such procedures. Expand