Most of colorectal adenocarcinomas are believed to arise from adenomas, which are premalignant lesions. Sequencing the whole exome of the adenoma will help identifying molecular biomarkers that can predict the occurrence of adenocarcinoma more precisely and help understanding the molecular pathways underlying the initial stage of colorectal tumorigenesis.… (More)
The ASAPM project aims at developing new techniques, mechanisms and software solutions for enablement of flexible, dynamic and robust management of service-oriented application provision processes to ensure collective functionality, end-to-end QoS and stateful coordination of complex services.
It is difficult to estimate solute transport parameters in streams empirically and numerous approaches have been investigated in the past. In the current study, we explored the use of the simulated annealing (SA) algorithm for estimating solute transport parameters in streams from tracer experiment data. For a simple one-dimensional dispersion test case,… (More)
Lung squamous cell carcinoma (SQCC) accounts for about 30% of all lung cancer cases. Understanding of mutational landscape for this subtype of lung cancer in Chinese patients is currently limited. We performed whole exome sequencing in samples from 100 patients with lung SQCCs to search for somatic mutations and the subsequent target capture sequencing in… (More)