L. Yu. Taros

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During the past 5 years, we have investigated in the Leningrad Pasteur Institute of Epidemiology the reactogenic and immunogenic properties, and also the epidemiologie effectiveness of 4 laboratory strains of the measles virus isolated in Leningrad from typical measles cases and studied during the process of prolonged passages on different tissue cultures(More)
A leading role in the formation of tissue barriers to the spread of infection is ascribed to the mononuclear phagocyte system, which can inactivate viral antigen and inhibit reproduction of the virus in the host cell [5, 8]. On the other hand, the effect of a viral antigen may be accompanied by depression of phagocytic activity [4, 8] and may ultimately(More)
Histopathological and, in particular, biochemical changes in the brain in herpetic infection have not yet been adequately studied [1-3, 12]. For instance, analysis of the state of the neuroglia has been confined to a description of the gliosis response. The possibility of investigating enriched fractions of neuroglia and neurons, whereby the role of each(More)
Clinical, morbid anatomical, and epidemiologic investigations have demonstratedthe aggravating effect of influenza infection on the course of diseases of the cardiovascular and nervous systems. Hence the urgency of the study of the mechanisms of action of influenza virus on nerve tissue in cases when a primary virus lesion develops, associated with changes(More)
An analysis of morbidity of the population in the course of 3 influenza A/Hong-Kong epidemics showed a pronounced decrease in influenza affection of adult population in the last epidemic in 1971--1972. Comparative studies of the diagnostic value of CFR and HIT demonstrated identical sensitivity of CFR as a method of influenza diagnostics in both the(More)
An immunological relationship between strains of influenza B virus, considerably differing from one another in haemagglutination inhibition (HI) and virus neutralization (VN) tests, was established. The relationships were also evaluated based on the ability of influenza B viruses to replicate in the lungs of mice immunized with strains possessing(More)
One and the same series of live influenza vaccine from the strains B/Dushanbe/66 and B/Leningrad/67 or A2/Moscow/21/65 administered intranasally to non-immune persons in Leningrad and 'krasnodar in winter caused an increase in body temperature in 6.7-8% of vaccinated subjects, but in summer in 0.8%. In the transitional seasons of the year (in May and in(More)
Inoculation with influenza A virus of nonpermissive cells from the immune system of Wistar rats was followed by an abortive reproduction cycle accompanied by the synthesis of viral polypeptides on the background of substantially decreased total protein synthesis. The de novo synthesized proteins in virus-infected immune system cells were shown to represent(More)
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