Learn More
The authors examined the effect of the piperasine derivative of 2-aminotetraline N-(trans-3-hydroxy--1,2,3,4-tetrahydro-2-naphthl)--N--(3-oxy-3-phenyl 1--2 methyl propyl)--piperasine (P11) on nobred white mice and rats of the Wistar strain and found interesting and specific neuropharmacological activity. The compound P11 inhibits the central nervous system,(More)
The studies have revealed that the type of gastric mucosa changes in the patients with duodenal ulcer correlates with the disease severity, and manifestations of the pathologic processes in the gastric mucosa depend on the stage of duodenal ulcer. The most grave changes in the gastric mucosa were revealed in the patients with hereditary predisposition to(More)
The authors performs studies under the conditions of whole organism in vivo and on isolatid organs in vitro and examined antihistamine and antiserotonine activity of two derivatives of 2-aminotetraline, synthesized by D. Dancev and Iv. Ivanov, namely: N-(trans-e-hydroxy-1, 2, 3, 4-tetrahydro-2-naphtyl (-N-) 3-oxo-3-phenylpropyl) piperasine dichloride and(More)