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A clinico-morphological study of ataxia-teleangiectasia permits to establish the depth and distribution of lesions. Morphological findings indicate to lesions mainly in the extrapyramidal system, cerebellum, subcortical structures and in the stem structures and spinal cord. Besides, there were changes in the hemispheres in the form of cell atrophy,(More)
Chronic progressive focal encephalitis or Rasmussen encephalitis (RE) is chronic brain disease of viral etiology. It is manifested by either partial motor or myoclonic seizures combined with hemiparesis. RE was described in detail in a girl of 8.5 years. The disease debut was observed at the age of 5.5 and manifested in the form of simple partial motor fits(More)
A sudden increase of temperature of surrounding medium, even in the sublethal range, induced in Amoeba proteus (strain War) and Amoeba borockensis the synthesis of a new class of proteins, which might be classified as the heat shock proteins (hsp). The new pattern of protein synthesis, determined by incorporation of (35)S-methionine, was detectable within(More)
The authors review both their own findings and literature data about chromosomal instability in neurologic diseases. The genetic mechanisms responsible for the development of chromosomal instability and its role in the pathogenesis of different diseases of the nervous system are discussed.
Electron microscopic study of the surface architectonics and ultrastructure of the peripheral blood erythrocytes in 25 children with insulin-dependent diabetes mellitus (IDDM) revealed that the decrease of the count of disk-shaped cells, increased count of transitional and degenerative forms, and alteration of their ultrastructure. Traditional therapy(More)