• Citations Per Year
Learn More
New, potential aldosterone blocking 17-spiro-oxazolidinone derivatives with androstane, estrane and 13 beta-ethyl-gonane ring system were synthesized. 17S-Spiro-oxiranes were used as starting compounds and the oxazolidinone ring was built up in different ways. All compounds but one were devoid of considerable endocrine activities. 3-Oxo-13(More)
GYKI-23 107 is a new antiarrhythmic substance with local anaesthetic activity. Its specific pharmacological and cardiovascular effects were studied in vivo and its efficacy was compared with that of lidocaine and mexiletine. GYKI-23 107 was effective against chemically (aconitine and ouabain) induced arrhythmias after both parenteral and oral(More)
Versuchen k o n n t e b i sher n i ch t festgestel l t , werdell : Der haploide, diploide u n d te t rap lo ide S ta tu re werden du rch A c t i n o m y c i n D in e twa d e m gle ichem AusmaB g e h e m m t . Ebenso k o n n t e ke in wesen t l i cher Un te r sch i ed zwischen der W i r k s a m k e i t you A c t i n o m y c i n D u n d A c t i n o m y c i n(More)