L. S. Sarkisova

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We have now synthesized some novel 5-methoxyindole-3-carboxylic acids with bromine in the 6-position of the ring (la, b). Decarboxylation of these compounds in quinoline has afforded 5-methoxy-6-bromolndoles with a free B-position (lla, b). These compounds, llke 4,5dimethoxy-6-bromoindole (llc) [2], are of interest as starting materials for the synthesis of(More)
In that connection we obtained derivatives of 4-oxybenzofuran with acetylaminomethyl substituents in position 3 of the benzofuran ring. The starting compounds were Mannich bases la-d [3] which were then subjected to acetylation, O-alkylation, and hydrolysis. We obtained the amides lla-d from the amines la-d through the action of acetic anhydride at 20*C.(More)
We have already shown that different substituted 1,2-naphthoquinones, including 6-halo1,2-naphthoquinones, exhibit an antiviral activity in experiments [i, 2]. These investigations led to the production of an original antiviral agent with a systemic action, i.e., 6-bromo-l,2,-naphthoquinone [3-6]. It is therefore interesting to study the antiviral activity(More)
i. V. V. Gatsura, Methods of Fundamental Pharmacological Research of Biologically Active Substances [in Russian], Moscow (1974), pp. 39-41. 2. I. N. Nazarov and V. A. Rubenko, Izv. Akad. Nauk SSSR, OXN, No. 6, 610-626 (1948). 3. I.N. Nazarov, N. S. Prostakov, and N. I. Shvetsov, Zh. Obshch. Khim., 26, 2798-2811 (1956). 4. I. N. Nazarov, N. S. Prostakov, N.(More)
Interactions of acryloyl chloride (compound I) with enaminocarbonyl compounds containing a secondary amino group are known to take place, reactions involving the secondary amino group, forming hydrogenated pyridone-2 compounds [1]. In the same conditions, tertiary enaminoketones and enaminoesters are converted to dihydroresorcine derivatives [2] or(More)
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