L S Pobegaĭlo

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In acute experiments on cats changes in the background sympathetic activity in the renal nerve, chosen as a model of vaso-constrictor nerve, together with arterial pressure shifts have been found following injections of nitric oxide (NO) containing drugs into the ventrolateral medulla. This is the first report of evidence that both sodium nitroprusside,(More)
These studies were designed to provide information on both GABA influences on the neuronal structures within the rostral ventrolateral medulla (RVLM) involved in the cardiovascular control, and fine structure of the GABA-sensitive RVLM in cats. By electron microscopy, the S-type asymmetric junctions (believed to mediate excitation) as well as F-type(More)
Data showing that GABA (0.5-50 mumols) injections into the neuronal structures of the caudal ventrolateral medulla (CVLM) being followed with hypertensive reactions induced by enhancement of the background activities of the renal and inferior cardiac nerves are obtained in acute experiments on cats. Inhibitory cardiac influences from the CVLM are realized(More)
The data obtained in acute experiments on cats have indicated that the most GABA-sensitive injected neuronal structures in the ventrolateral medulla appear to be located in the vicinity to the roots of the XII cranial nerves. GABA injected into these structures just rostrally to the roots induced hypotensive reactions due to heart rate and myocardial(More)
Acute experiments in cats revealed effects of GABA injections (2.10(-5)-5.10(-5) M/l) into the neuronal structures of the dorso-medial medulla after M-cholinoreceptors had been blocked. Hypotensive action of GABA injected into the n. ambiguous and ventral reticular nucleus was shown to be actualized through participation of bulbar M-cholinoreceptors.(More)
Some differences in the location of supposedly inhibitory synapses (F-type) have been revealed in the course of the study of the ultrastructural organization of the chemosensitive ventrolateral medulla in the cat at the level 2-6 mm caudally of trapezoid bodies. These synapses are formed by axon terminals filled with flattened synaptic vesicles whose long(More)
Acute experiments in cats revealed GABA-sensitive neurons in the chemosensitive area of the bulbar ventrolateral surface. Microinjections of GABA (1 X 10(-5)-5 X 10(-4) mol/l) into these bulbar structures produced consistent inhibition of efferent activity in renal nerves involved in maintenance of the arterial pressure level, heart rate and vascular tonus(More)
In acute experiments on cats, microinjections of 2 micrograms of serotonin to the nucleus of tractus solitarii and to the ventral reticular nucleus brought about remarkable and consistent changes in renal sympathetic activity. The test nuclei were shown to contain serotoninoceptive neurons. Serotonin activation of the neurons led to the potentiation of(More)
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