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A human lung carcinoma cell line, UCP3, was carried as subcutaneous xenotransplants in athymic mice. Autopsies of these animals showed rare foci of microscopically visible metastases to any of the other organs. A metastatic variant, 522, was established serendipitously in vitro as a continuous cell line by blind isolation of the pulmonary metastatic foci,(More)
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