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  • Burgering, B M T Bos, +27 authors R J Gbg
  • 1997
in vitro and in vivo association assays. The GST–cytoplasmic region of EGFR fusion proteins (amino acids 930–1,220, which do not include Lys 721, a key residue in the ATP-binding site) were generated as described 28. The in vitro Jak2 assay was done as before 2 , with minimal modification. Proteins immobilized on anti-Jak2 antibody were mixed with 95 ␮l of(More)
We propose a constructive approach to building single-hidden-layer neural networks for nonlinear function approximation using frequency domain analysis. We introduce a spectrum-based learning procedure that minimizes the difference between the spectrum of the training data and the spectrum of the network's estimates. The network is built up incrementally(More)
The fifth author's first and last names were inadvertently switched. The first name appears as the last name and the last name appears as the first name. The correct name is: Tadepally Lakshmi-kanth. The correct citation is: open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use,(More)
grade astrocytic tumors comparable in scope yet greater in magnitude to that of the prior 40 years. This is thanks to the convergence of three factors: the introduction of an oral agent with antitumor activity beyond the blood–brain barrier and modest systemic toxicity (temozolomide); the demonstration through a well-conducted randomized trial of the(More)
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