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Transbronchial forceps biopsy through the fiberoptic bronchoscope was performed in 37 patients. Tissue was technically inadequate for examination in two cases. A pathologic diagnosis was obtained in 26 (72 percent) and in five additional critically ill patients, direct histologic examination of lung tissue allowed exclusion of certain entities, thus(More)
In a prospective study at two medical centers, 42 consecutive patients with suspected sarcoidosis underwent transbronchial lung biopsy during fiberoptic bronchoscopy. Transbronchial biopsy revealed noncaseating granulomas in 24 of the 38 cases (63%) in which adequate tissue was obtained. Special stains and cultures for acid-fast bacilli and fungi were(More)
Small caliber needle aspiration of lung lesions has been successfully and safely used for diagnostic purposes. We report our initial experience using computed tomography-guided fine needle percutaneous implantation for direct intralesional high-dose rate brachytherapy for malignant pulmonary lesions. Twenty patients with primary lung cancer or metastatic(More)
We report the results of the treatment of 45 patients (38 with malignant and seven with benign disease) with intrabronchial lesions using the neodymium-YAG laser via the flexible fiberoptic bronchoscope. Multiple treatment sessions were used with treatment intervals varying from four days to four weeks. Additional debridement procedures were also necessary(More)
The development of a bronchopleural fistula (BPF) is an infrequent, but potentially devastating complication of positive pressure ventilation. A case report is detailed in which a BPF arose in a patient on controlled ventilation with a PEEP of 22 cm H2O. Within 12 hours, fistula flow was continuous and accounted for 75% of the delivered tidal volume. PEEP(More)
We produced a pneumothorax on the left side in rabbits and measured the oxygen consumption of lung slices from previously collapsed left and non-collapsed right lung immediately after in vitro re-expansion. After re-expansion, the oxygen consumptions of the previously collapsed and non-collapsed lung were almost identical, 162 +/- 6.7 and 168.6 +/- 9.6(More)
We studied the oxygen consumption (QO2) of lung slices and the ultrastructure of the pulmonary granular pneumocyte in rats whose level of circulating thyroxine was altered. Rats given thyroxine for 6 days (1.0 mg-kg-1-day-1) and sacrificed on the 7th day had a serum thyroxine level of 18.9 +/- 2.7 mug/100 ml (mean +/- SD); rats given diluent alone for 6(More)
From March 1, 1984, to Nov. 1, 1985, six patients underwent pleuroperitoneal shunting for either malignant (n = 5) or benign (n = 1) effusions intractable to the usual therapy. A modified double-valve Denver peritoneovenous shunt was inserted under local anesthesia in each case, and fluid from the right or left pleural space was shunted to the subhepatic(More)