L. R. Adkison

Learn More
A repetitive DNA sequence, MS2, was isolated from EcoRI-digested genomic DNA of the vole, Microtus subarvalis. The fragment was cloned and sequenced. Sequence analysis of this 1194-bp fragment revealed a 156-bp region demonstrating a 55% homology with the mouse B1 repeat. The remaining MS2 sequence shows no significant homology with other known Gen-Bank(More)
The genus Triticum L. includes the major cereal crop, common or bread wheat (hexaploid Triticum aestivum L.), and other important cultivated species. Here, we conducted a phylogenetic analysis of all known wheat species and the closely related Aegilops species. This analysis was based on chloroplast matK gene comparison along with trnL intron sequences of(More)
Several LINE-1s have been isolated and characterized from genomic DNA of the vole, Microtus kirgisorum. Blot hybridization revealed specific restriction patterns of L1 elements in vole genomes. Rehybridization of the genomic blot with a cloned 5′-end fragment revealed two major bands indicating the presence of two different L1 subfamilies. The copy numbers(More)
Retrotransposons are the major component of plant genomes. Chromodomain-containing Gypsy long terminal repeat (LTR) retrotransposons are widely distributed in eukaryotes. Four distinct clades of chromodomain-containing Gypsy retroelements are known from the vascular plants: Reina, CRM, Galadriel and Tekay. At the same time, almost nothing is known about the(More)
The basic structure of the erythrocyte membrane skeleton is a polygonal lattice created by the cross-linking of short actin filaments by long spectrin beterotetramers. This actin protofilament and its accessory proteins (tropomyosin, tropomodulin, adducin, protein band 4.1, protein band 4.9) have been called the junctional complex (reviewed in Gilligan and(More)
1Section of Genetics, Children's Mercy Hospital/UMKC School of Medicine, Kansas City, Missouri 64108, USA 2Division of Biomedical Sciences, Mercer University School of Medicine, Macon, Georgia 31207, USA 3Division of Hematology/Oncology, Children's Hospital and Harvard Medical School, Boston, Masschusetts 02115, USA 4Department of Pathology, Boston(More)
Extracellular matrix proteins are well characterized for their involvement in cell adhesion, cell growth control, and development. These proteins comprise a family of cell surface molecules, collectively known as integrins. While their functions appear dissimilar, these molecules are structurally similar (Hynes 1987). They are heterodimeric complexes(More)
DNA polymerase (pol) eta participates in hypermutation of A:T bases in Ig genes because humans deficient for the polymerase have fewer substitutions of these bases. To determine whether polymerase eta is also responsible for the well-known preference for mutations of A vs T on the nontranscribed strand, we sequenced variable regions from three patients with(More)
The presence of repetitive elements can create serious problems for sequence analysis, especially in the case of homology searches in nucleotide sequence databases. Repetitive elements should be treated carefully by using special programs and databases. In this paper, various aspects of SINE (short interspersed repetitive element) identification, analysis(More)
OBJECTIVE The objective was to test the reliability of new deoxyribonucleic acid primers that have previously been used very efficiently by this laboratory with amniolysate samples to amplify a 248 bp Y-specific, repeated sequence from maternal blood during pregnancy. STUDY DESIGN Blood samples were obtained from 50 women during weeks 11 and 16 of(More)