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Striated muscle activity is always accompanied by oxidative stress (OxStress): the more intense muscle work and/or its duration, the more a redox imbalance may be attained. In spite of cardiac muscle functioning continuously, it is well known that the heart does not suffer from OxStress-induced damage over a broad physiological range. Although the(More)
Moderate physical activity when performed on a regular basis presents a number of benefits to the whole organism, especially regarding immune system function, such as augmenting resistance to infections and to cancer growth. Although glutamine production by active muscle cells as well as neuroendocrine alterations mediated by the chronic adaptation to(More)
What features characterize complex system dynamics? Power laws and scale invariance of fluctuations are often taken as the hallmarks of complexity, drawing on analogies with equilibrium critical phenomena. Here we argue that slow, directed dynamics, during which the system's properties change significantly, is fundamental. The underlying dynamics is related(More)
Colorectal cancer (CRC) is a major public health problem worldwide, with a current annual incidence approaching 950,000 cases. Around 3–5% of all CRC cases are recognized as hereditary non-polyposis colorectal cancer (HNPCC), or Lynch Syndrome (LS), which is an inherited syndrome predisposing to the early development of cancers of colon, rectum,(More)
A new full-vectorial finite element method (FEM) approach completely free of spurious modes for analyzing photonic structures is presented. The new formulation incorporates the divergence-free condition into the vectorial wave equation, producing a highly well-conditioned and straightforward modal-analysis algorithm.
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