L. P. Kopytovskaia

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Utilization of the anaphylactic reaction for distinguishing tumor antigens from antigens of normal tissues requires the preliminary investigation of 2 problems: 1) how should desensitization against “major” antigens be performed in order to be sure of its completeness, and 2) how does such desensitization affect the sensitivity of the animal to “minor”(More)
Adrenalectomized mice may develop local (skin) and systemic reactions on the introduction of immune complexes formed in vitro. Regularities in respect to the composition of immune complexes (in which their general, toxic, action and the capacity to produce local reactions was expressed) were revealed. Treatment with agents depressing the anaphylactic(More)
Serological criteria for detection of the circulating immune complexes and for a possible evaluation of a comparative expression of the corresponding pathological process were investigated. Foreign serum was repeatedly administered to rabbits against the background [corrected] of the circulating anyibodies. A study was made of the three serological indices(More)
Experiments were conducted on mongrel albino mice; a study was made of the role played by the complement in the development of passive skin anaphylaxis after Ovarie and the so called reverse direct allergic (cytotoxic) reaction. Preliminary animal decomplementation 3 hours before the reactions were conducted failed to alter the intensity of Ovarie reaction,(More)