L N Anderson

Learn More
Violence in society is reflected in aggressive acts within health care delivery systems. As health care reform continues to emphasize preventive health, primary health care settings will increasingly be used to deliver preventive care and may experience an increase in episodes of aggressive behaviors. Verbal abuse is the most common form of aggression, with(More)
The application of microchip capillary electrophoresis (CE) to the assay of extracellular signal-regulated protein kinase (ERK) is presented. In this assay, ERK catalyzes the transfer of gamma-phosphate from adenosine 5(')-triphosphate to the threonine residue of a fluorescently labeled nonapeptide (APRTPGGRR), and the phosphorylated and nonphosphorylated(More)
Multiplexed (96-lane) capillary electrophoresis with laser-induced fluorescence (MCE-LIF) detection was used for the rapid analysis of extracellular signal-regulated protein kinase (ERK) levels from in vitro cell extracts. The levels of ERK enzyme in cell extracts were determined by monitoring the conversion of a fluorescent-labeled peptide substrate to a(More)
State College, Pennsylvania). A few reports have addressed the development, characterization, and application of multiplexed CE for enzyme analysis, combinatorial screening of catalysis reaction conditions, the analysis of small organic molecules, and peptide mapping (22–26). We evaluated the performance of multiplexed CE with laser-induced fluorescence(More)
  • 1