Learn More
Golgi-Stensaas and rapid-Golgi staining techniques are used to study neuronal differentiation in the developing human prefrontal cortex in fetuses, premature infants, and full-term newborns from 10.5 to 40 weeks of gestation. Horizontal neurons (Cajal-Retzius neurons) above the cortical plate (in the marginal zone) and randomly oriented neurons below the(More)
The present study shows that in the prenatal rat neocortex the GABA immunoreactive neurons are not limited to the marginal, subplate, and intermediate zones, but are also found in all fetal zones of the cerebral anlage. The first GABA-ergic cells are observed on embryonic day 14 in the plexiform primordium. On embryonic day 15, a second population of(More)
The quantitative development of neurons in the human dorsolateral and lateral prefrontal cortex was studied in Golgi-impregnated tissue from postmortem brains ranging from 13.5 weeks of gestation up to the second postnatal month. Pyramidal neurons in the future layers III and V of the cortical plate, as well as different types of neurons in the transient(More)
The small magnocellular group located within the rostrolateral extension of the basal forebrain was named and described as the nucleus subputaminalis in the human and chimpanzee brain by Ayala. Analysis of cytoarchitectonic and cytochemical characteristics of this cell group has been largely disregarded in both classical and more current studies. We(More)
The developmental status of some potential components of hippocampal circuitry was studied at the time of the emergence of the hippocampal cytoarchitectonic subfields. The laminar distribution of synapses as seen with electron microscopy was correlated with Golgi architectonics in 15- and 16.5-week-old human fetuses. A systematic electron microscopic(More)
The sequential development and growth of the subcortico-cortical fibres have been studied by means of acetylcholinesterase (AChE; acetylcholine acetylhydrolase; EC 3.1.1.7) histochemistry on the serial sections obtained from brains of human fetuses ranging from 10 to 28 weeks of gestation. It was found that thalamic and basal telencephalic fibres(More)
The aim of this study was to analyze the granule cell population of the dentate gyrus both in healthy rhesus monkeys and in humans free of mental and neurological disorders. Brains of neonatal and adult rhesus monkeys as well as brains of fetal, neonatal and adult humans were impregnated with Golgi methods. The results show that a significant population of(More)
Mossy cells in the human dentate gyrus of adults and children of different ages were impregnated using the rapid-Golgi method. In every case the cause of death was verified by autopsy and the brains were used when neither the history of the patient nor autopsy revealed brain-related disease. Mossy cells in the human share common light microscopic features(More)
In this study we examined the morphological maturation of the basal dendritic field of layer III pyramidal neurons located in the human dorsolateral prefrontal cortex in subjects ranging from 7.5 months after birth up to 27 years. The sections were stained with the Golgi-Cox method and the three-dimensional branching pattern was measured with a(More)