L M van Leeuwen

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BACKGROUND After high-dose chemotherapy with autologous stem-cell support long hospital stays in the aplastic phase are expensive, lead to increased risk of hospital infections and to increasing pressure on available hospital beds. We developed a home care regimen that allows patients to be at home for most of the aplastic period, without daily hospital(More)
Perceiving the affordance of a tool requires the integration of several complementary relationships among actor, tool, and target. Highers order affordance structures are introduced to deal with these forms of complex action from an ecological-realist point of view. The complexity of the higher order affordance structure was used to predict the difficulty(More)
PURPOSE To gain qualitative insight into the rehabilitation needs of visually impaired young adults (18-25 years) and how these needs relate to the International Classification of Functioning, Disability and Health (ICF) and patient characteristics. METHODS Rehabilitation needs and patient characteristics of young adults (N = 392) who applied for(More)
Sufentanil 3 microgram kg-1 was administered as an intravenous (i.v.) bolus to 12 elderly patients, aged 65-87 years and 12 young adults, 17-43 years of age, all ASA class I-II, scheduled for orthopaedic surgery. Plasma sufentanil concentrations were measured by a specific radioimmunoassay. Plasma concentration time-curves for the young adult and the(More)
Long-term complete remission in IgD multiple myeloma (MM) is rare. This case report describes a patient with a stage IIIB IgD-MM, who was treated with conventional melphalan and prednisone chemotherapy. The monoclonal protein disappeared after four cycles and therapy was discontinued after 14 cycles. Re-evaluation after a follow up of more than 8 years(More)
This study evaluated recovery after a fixed dose of midazolam as induction agent and the influence of flumazenil on recovery parameters in patients undergoing day-case surgery (arthroscopy of the knee). In 40 unpremedicated patients, anaesthesia was induced with midazolam 0.2 mg/kg, vecuronium bromide 0.1 mg/kg intravenously and 3 vol.% isoflurane in oxygen(More)
To develop a comprehensive, conceptual model detailing the aspects of a child’s life (<18 years) that are affected by low vision. Three stakeholders were involved in the developmental process of the conceptual model: children and adolescents with a visual impairment (n = 40), parents of children with a visual impairment (n = 25) and professionals of(More)
Atracurium 0.5 mg.kg-1 and vecuronium 0.1 mg.kg-1 were compared as neuromuscular relaxants for outpatient arthroscopy of the knee under general anaesthesia. In 40 unpremedicated patients divided at random into two groups, anaesthesia was induced with methohexitone, atracurium (Group A) or vecuronium (Group B), three per cent isoflurane prior to intubation(More)
The proposed procedure offers a method of evaluation that is feasible, but still a very precise method, for the evaluation of electronic differential leukocyte counters. Following this abbreviated method, the classification of the leukocytes, from 5 x 20 unselected blood specimens, with a flow-cytometric analysis by the Sequoia Turner Cell-Dyn 3000, was(More)
Propofol by continuous intravenous infusion has been compared with isoflurane as the main anaesthetic agent for outpatient arthroscopy of the knee. In 40 unpremedicated patients, anaesthesia was induced with propofol 2 mg/kg and vecuronium bromide 0.1 mg/kg and maintained after tracheal intubation with nitrous oxide 66% in oxygen. One group received 3%(More)