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Histamine accumulated in the ligated vagus nerve of the rat, both above and below the ligature; maximum accumulation was after 4 h. The finding is suggestive of axonal flow. Further evidence for histamine in peripheral nerves was obtained in experiments showing that the guinea-pig gut wall could be labelled with [3H]histamine. The experiments were carried(More)
The aim of the present study was to investigate whether plasma levels of gastrin, somatostatin, insulin, oxytocin, VIP and blood glucose levels vary during the menstrual cycle. Therefore, 19 healthy menstruating women (5 of whom were on low-dose oral contraceptives, o.c.) were blood sampled every second to third day during the menstrual cycle. Hormone(More)
When female Saccostomus campestris are stressed during pregnancy they may resorb part of the litter. Resorption can take place on more than one occasion during the same pregnancy without affecting the development of the rest of the litter. The last resorption may be initiated as late as 72-48 h before parturition. No other rodents with a similar gestation(More)
The capacity for steroid production in the corpora lutea (CL) of bank voles was examined by enzyme histochemistry for 3 beta-hydroxysteroid dehydrogenase. The results revealed similar activity in the CL resulting from sterile matings and the CL of pregnancy 2 days after mating. Six days after mating, the CL of pregnancy showed a strong reaction, while there(More)
Sexual development in male Saccostomus campestris, the pouched mouse, was studied in terms of morphological development and changes in concentrations of plasma testosterone and androstenedione. The interaction of adult females and males following the introduction of a male was observed at all stages of the oestrous cycle. The histology of the reproductive(More)
Regulation of corpus luteum function was studied in pouched mice, housed under controlled conditions (14L:10D), (22 +/- 2 degrees C). Prolactin in daily doses of 32 IU promoted luteal and uterine development and markedly increased plasma levels of progesterone in females exhibiting estrous cycles. Negligible levels of progesterone in prolactin-treated(More)
Female bank voles mated when 30-50 days old showed only 20-25% fertility at the first mating, but fertility increased to about 80% in animals greater than 100 days of age at the first mating. Young females subjected to artificial cervical stimulation after the completion of a normal mating showed a much higher fertility than normally mated controls (76(More)
Between 30 and 40 days of age, female bank voles were kept singly, in female pairs, separated from an adult male by a wire mesh, or paired with a vasectomized male. At Day 40 they were paired with adult intact males. Fertility at the first mating was low (22-25%), but if the females had previously mated with the vasectomized male fertility of the subsequent(More)
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