L. M. Paoletti

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Bacterial cells exert exquisite control over the biosynthesis of their membrane lipids, but the mechanisms are obscure. We describe the identification and purification from Bacillus subtilis of a transcription factor, FapR, that controls the expression of many genes involved in fatty acid and phospholipid metabolism (the fap regulon). Expression of this fap(More)
During the late stages of the HIV-1 replication cycle, the viral polyprotein Pr55(Gag) is recruited to the plasma membrane (PM), where it binds phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) and directs HIV-1 assembly. We show that Rab27a controls the trafficking of late endosomes carrying phosphatidylinositol 4-kinase type 2 α (PI4KIIα) toward the PM of(More)
An epidemiological study (Paci et al., 1987) showed that among thirteen pleural malignant mesothelioma (PMM) cases incident in the Province of Florence during the years 1979-1984, there were six cases who had been workers in the textile industry in the Prato area, five of them in a particular job, the sorting of rags. In this area of the Province of(More)
Neuronal differentiation plays a key role during embryogenesis. However, based on the capacity of neuronal stem cells to either generate or regenerate neurons and because differentiation stops aberrant neuroblasts proliferation, neuronal differentiation is crucial during neuropathological conditions. Although phosphatidylcholine (PtdCho) has been proposed(More)
This article compares the presence of solid particles in lung parenchyma samples collected from accident victims and in bronchoalveolar lavage fluid taken from patients diagnosed with pulmonary carcinoma. Analysis by electron microscopy showed differences in particle size between the two groups, which could be attributable both to differences in original(More)
The Department of Defense (DoD) is one of the biggest users of communications in the world. Communications systems are used not only for the administration of the Department, but, most critically, for the command and control of force structures. To this end, the Defense Communications Agency (DCA) strives to ensure that the Department's missions are carried(More)
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