L. M. Gershtein

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slightly. In arterioles it dropped only 8% on average. The hemodynamic response of individual arterioles was heterogeneous, probably due to the mesenteric angioarchitectonics. The polymer lowered blood pressure in radial arteries by 19.4 and 18.4% (in comparison with the period before and after administrat ion of adenosine, respectively); AP dropped by(More)
The complex neurophysiological, biochemical, and histochemical investigation carried out in dogs, cats, rabbits, and rats revealed the effects of taftsin (300 mcg/kg) at the macro- and microlevels within different periods (30 and 75 min) after its intraperitoneal injection. It was shown that after taftsin administration the configuration of evoked(More)
Many years' studies in functional neurochemistry have provided a concept of the functionally induced biochemical heterogeneity of neurons and their subcellular components, which is formed during ontogenesis as the functions of the central nervous system are developed. It has been established that it manifests itself at the systemic, cellular, and(More)
Differences have been found in responses of the brain formations studied by some protein metabolic parameters. They manifest themselves both between the neurons of cortical and subcortical structures and between those of various morphofunctional types and affect the corrective action of delta-sleep peptide.
The resulting data give evidences, that after injection of the low doses of amphetamine the decrease of amplitudes both negative (NC-3), and positive components (PC-3) of the thalamo-cortical responses (TCR) of the sensorimotor cortex (SMC) takes place in 2nd-3d-weeks-old rabbits of their postnatal life. At the same time the amplitudes of these phases in(More)
Interferometrically is was shown that the absence of visual impulsation from the very birth of the animal caused alterations in protein substances not only in the neurons of visual area of the brain cortex but also in those of the motory one. However, unlike the visual area with the alteration of the deficience type (lowered protein contents, reduced(More)
The systemic injection of haloperidol (4 wk, 0.5 mg/kg/d) caused the increase of protein concentration and content, and the activity level of aminopeptidase in the cytoplasm of the neurons of associated type (layer III). The nucleus of these cells decreased both in sizes and in the content of proteins. In the neurons of efferent-projectory type (layer V),(More)
In the course of a long-term L-DOPA administration (14 days) and 2 weeks after its cessation the activities of some protein enzymes (aminopeptidase, acid phosphatase), neuromediator (MAO, ACE) and oxidative (glutamate dehydrogenase, glucose-6-phosphate dehydrogenase) metabolism were studied by quantitative cytochemical methods in brain motor structures(More)
Histological investigation was carried out to study the activity of aminopeptidase (AMP) in neurons of the nodose ganglion of immobilized rabbits with acute experimental emotional stress induced by electrical stimulation of ventromedial hypothalamic nuclei and skin. On the basis of the pattern of cardiovascular reactions, two groups of animals were(More)