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The modified Telephone Interview for Cognitive Status (TICS-m) is a widely used screening instrument for (Alzheimer's) dementia. Psychometric evaluation of the TICS-m is limited. This study examined the relation between the TICS-m and a comprehensive neuropsychological assessment in older persons (n = 243) without cognitive deficits. The TICS-m total score(More)
This article describes a standardized administration and scoring procedure for the widely used Corsi Block-Tapping Task, designed to assess the visual memory span. This method was applied in a group of healthy participants (n = 70) and a group of patients with cerebral lesions (n = 70), that were categorized on the basis of lesion location (left or right(More)
The structural correlates of impaired cognition in type 2 diabetes are unclear. The present study compared cognition and brain magnetic resonance imaging (MRI) between type 2 diabetic patients and nondiabetic control subjects and assessed the relationship between cognition and MRI findings and blood pressure and metabolic control. The study included 113(More)
Spatial working memory entails the ability to keep spatial information active in working memory over a short period of time. To study the areas of the brain that are involved in spatial working memory, a group of stroke patients was tested with a spatial search task. Patients and healthy controls were asked to search through a number of boxes shown at(More)
BACKGROUND In patients with acute ischemic stroke caused by a proximal intracranial arterial occlusion, intraarterial treatment is highly effective for emergency revascularization. However, proof of a beneficial effect on functional outcome is lacking. METHODS We randomly assigned eligible patients to either intraarterial treatment plus usual care or(More)
BACKGROUND AND PURPOSE Information about the long-term prognosis of young adults with ischemic stroke is limited. Therefore, we performed a follow-up assessment of 296 patients with ischemic stroke who are enrolled in the Iowa Registry of Stroke in Young Adults. We studied young adults (age, 15 to 45 years) who were referred to a tertiary medical center for(More)
BACKGROUND AND PURPOSE The goal of this study was to examine the hypotheses that retinal ischemia is caused more often by carotid atherosclerosis than by atrial fibrillation and that the odds of retinal events compared with hemispheric events increase with worsening carotid stenosis. METHODS We used data from the Stroke Prevention in Atrial Fibrillation(More)
BACKGROUND AND PURPOSE Arterial disease resulting in cerebral ischemia can be classified into large vessel disease (LVD) and small vessel disease (SVD). We assessed whether antiplatelet drugs were more efficacious in large than in small vessel cerebrovascular disease. METHODS Individual patient data of the second European Stroke Prevention Study (n=6602),(More)
BACKGROUND AND PURPOSE Diffusion-weighted MRI (DWI) is highly sensitive in detecting early cerebral ischemic changes in acute stroke patients. In this study we compared the sensitivity of DWI with that of conventional MRI techniques. Furthermore, we investigated the prognostic value of the volume of ischemic lesions on DWI scans and of the apparent(More)
OBJECTIVE To examine the relation between depressive symptoms and specific cognitive functions in patients with a recent stroke and to examine associations with lesion characteristics. METHODS We studied 126 of 183 consecutive patients within 3 weeks after a first-ever symptomatic stroke (mean interval, 8.3+/-4.3 days). Presence and severity of depressive(More)